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dopamine Hydrochloride in 5% dextrose injection, USP

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dopamine Hydrochloride in 5% dextrose injection, USP Quick Finder

HIGHLIGHTS OF PRESCRIBING INFORMATION

These highlights do not include all the...
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1 INDICATIONS AND USAGE

Dopamine Hydrochloride in Dextrose Injection is indicated to improve hemodynamic status in patients in distributive shock, or shock due to reduced cardiac output.

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2 DOSAGE AND ADMINISTRATION

2.1 Administration Instructions

Correct Hypovolemia, Acidosis,...

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3 DOSAGE FORMS AND STRENGTHS

The following strengths of Dopamine Hydrochloride in 5% Dextrose Injection, USP, are supplied in LifeCare flexible single-dose plastic containers (the solutions are clear to slightly yellow in...

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4 CONTRAINDICATIONS

Dopamine is contraindicated in patients with pheochromocytoma.

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5 WARNINGS AND PRECAUTIONS

5.1 Tissue Ischemia

Administration of dopamine to patients who are hypotensive from hypovolemia can result in severe peripheral and...

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7 DRUG INTERACTIONS

See

...
Table 1: Clinically Significant Drug Interactions with Dopamine
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8 USE IN SPECIFIC POPULATIONS

8.1 Pregnancy

Risk Summary

There are no human data...

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10 OVERDOSAGE

Manifestations of overdosage include excessive blood pressure elevation.

In the case of accidental overdosage, reduce rate of Dopamine HCl in Dextrose Injection infusion, or temporarily discontinue the...

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11 DESCRIPTION

Dopamine Hydrochloride in 5% Dextrose Injection, USP is a sterile, nonpyrogenic, premixed solution of dopamine hydrochloride in 5% dextrose injection for intravenous infusion.

Each 100 mL contains 80...

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12 CLINICAL PHARMACOLOGY

12.1 Mechanism of Action

Dopamine is a natural catecholamine formed by the decarboxylation of 3,4-dihydroxyphenylalanine (DOPA). It is a...

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13 NONCLINICAL TOXICOLOGY

13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility

...

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16 HOW SUPPLIED/STORAGE AND HANDLING

Dopamine Hydrochloride in 5% Dextrose Injection, USP, is supplied in 250 and 500 mL LifeCare flexible single-dose plastic containers (the solutions are clear to slightly yellow in...

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17 PATIENT COUNSELING INFORMATION

Risk of Tissue Damage

Advise the patient, family, or caregiver to report signs of extravasation...

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