Medical Information
United States
 

In order to provide you with relevant and meaningful content we need to know more about you.

Please choose the category that best describes you.

Existe información en español para pacientes y cuidadores, para acceder, haga clic sobre “Select” al lado de “I am a U.S. Patient / Caregiver”.

This content is intended for U.S. Healthcare Professionals. Would you like to proceed?

If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.

Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.

bupivacaine hydrochloride injection, USP - SPINAL

If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.

Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.

bupivacaine hydrochloride injection, USP - SPINAL Quick Finder

HIGHLIGHTS OF PRESCRIBING INFORMATION

These highlights do not include all the...
Did you find an answer to your question? Yes No

1 INDICATIONS AND USAGE

BUPIVACAINE SPINAL is indicated for subarachnoid injection in adults for the production of subarachnoid block (spinal anesthesia).

Did you find an answer to your question? Yes No

2 DOSAGE AND ADMINISTRATION

2.1 Important Dosage and Administration Information

Visually inspect this product for particulate matter and discoloration prior to...
Did you find an answer to your question? Yes No

3 DOSAGE FORMS AND STRENGTHS

BUPIVACAINE SPINAL (bupivacaine hydrochloride in dextrose injection) is a clear, colorless solution available as:

15 mg/2 mL (7.5 mg/mL) in single-dose glass ampules.
...
Did you find an answer to your question? Yes No

4 CONTRAINDICATIONS

BUPIVACAINE SPINAL is contraindicated in:

intravenous regional anesthesia (Bier Block) [see Warnings and...
Did you find an answer to your question? Yes No

5 WARNINGS AND PRECAUTIONS

5.1 Use of Spinal Anesthetics During Uterine Contractions

Spinal anesthetics including BUPIVACAINE SPINAL should not be injected during...

Did you find an answer to your question? Yes No

6 ADVERSE REACTIONS

The following clinically significant adverse reactions have been reported and described in other sections of the labeling:

Allergic-Type Reactions [see...
Did you find an answer to your question? Yes No

7 DRUG INTERACTIONS

7.1 Local Anesthetics

The toxic effects of local anesthetics are additive. If coadministration of other local anesthetics with BUPIVACAINE...

Did you find an answer to your question? Yes No

8 USE IN SPECIFIC POPULATIONS

8.1 Pregnancy

Risk Summary

The available data on the use of BUPIVACAINE SPINAL in pregnant women...

Did you find an answer to your question? Yes No

10 OVERDOSAGE

Clinical Presentation

Acute emergencies from BUPIVACAINE SPINAL are generally related to hypoventilation (and perhaps apnea) secondary to upward extension of spinal...

Did you find an answer to your question? Yes No

11 DESCRIPTION

BUPIVACAINE SPINAL (bupivacaine hydrochloride in dextrose injection) is an amide-local anesthetic and sterile hyperbaric aqueous solution. The route of administration for BUPIVACAINE SPINAL is by subarachnoid...

Did you find an answer to your question? Yes No

12 CLINICAL PHARMACOLOGY

12.1 Mechanism of Action

Bupivacaine blocks the generation and the conduction of nerve impulses, presumably by increasing the threshold for...

Did you find an answer to your question? Yes No

13 NONCLINICAL TOXICOLOGY

13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility

Carcinogenesis

Long-term studies in animals...

Did you find an answer to your question? Yes No

16 HOW SUPPLIED/STORAGE AND HANDLING

Store at 20°C to 25°C (68°F to 77°F); excursions permitted between 15°C to 30°C (59°F to 86°F). [See USP Controlled Room Temperature.]

BUPIVACAINE SPINAL solution may be autoclaved...

Did you find an answer to your question? Yes No

17 PATIENT COUNSELING INFORMATION

Allergic-Type Reactions

Assess if the patient has had allergic-type reactions to amide-type local anesthetics or to other formulation ingredients...

Did you find an answer to your question? Yes No
Did you find an answer to your question? Yes No
Didn’t find what you were looking for? Contact us.
Report Adverse Event