Pemetrexed Injection is a folate analog metabolic inhibitor indicated:
Injection: 100 mg/4 mL (25 mg/mL) in a single-dose vial (3) Injection: 500 mg/20 mL (25 mg/mL) in a single-dose vial (3) Injection: 1 g/40 mL (25 mg/mL) in a single-dose vial. (3)
History of severe hypersensitivity reaction to pemetrexed. (4)
To report SUSPECTED ADVERSE REACTIONS, contact Pfizer Inc., at 1-800-438-1985 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Ibuprofen increased risk of Pemetrexed Injection toxicity in patients with mild to moderate renal impairment. Modify the ibuprofen dosage as recommended for patients with a creatinine clearance between 45 mL/min and 79 mL/min. (2.5, 5.6, 7)
Lactation: Advise not to breastfeed. (8.2)
See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling.
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