What are possible side effects of VFEND?
- liver problems. Symptoms of liver problems may include:
| - itchy skin
- flu-like symptoms
| - yellowing of your eyes
- nausea or vomiting
| |
- vision changes. Symptoms of vision changes may include:
- blurred vision
- changes in the way you see colors
- sensitivity to light or sun (photosensitivity). VFEND can cause serious photosensitivity. There is an increased chance of skin toxicity while taking VFEND. This can happen with or without taking other medicines like methotrexate. Photosensitivity reactions may also increase your risk of:
- faster skin aging from the sun
- skin cancer
Call your healthcare provider right away if you get a new skin rash or your skin rash gets worse. - serious heart problems. VFEND may cause changes in your heart rate or rhythm, including your heart stopping (cardiac arrest).
- allergic reactions. Symptoms of an allergic reaction may include:
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| - fever
- chest tightness
- nausea
| - sweating
- trouble breathing
- itching
| - feels like your heart is beating fast (tachycardia)
- feel faint
- skin rash
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- kidney problems. VFEND may cause new or worse problems with kidney function, including kidney failure. Your healthcare provider should check your kidney function while you are taking VFEND. Your healthcare provider will decide if you can keep taking VFEND
- serious skin reactions. Symptoms of serious skin reactions may include:
- rash or hives
- mouth sores
- blistering or peeling of your skin
- trouble swallowing or breathing
- adrenal gland problems:
- VFEND may cause reduced adrenal function (adrenal insufficiency).
- VFEND may cause overactive adrenal function (Cushing's syndrome) when voriconazole is used at the same time with corticosteroids.
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| Symptoms of adrenal insufficiency include: |
| - feeling tired
- nausea and vomiting
- abdominal pain
| - lack of energy
- feeling dizzy or lightheaded
| |
| Symptoms of Cushing's syndrome include: |
| - weight gain
- thinning skin
- excessive hair growth
| - fatty hump between the shoulders (buffalo hump) and a rounded face (moon face)
- bruising easily
- excessive sweating
| - darkening of the skin on the stomach, thighs, breasts, and arms
- high blood sugar
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- bone problems. VFEND may cause weakening of bones and bone pain. Tell your healthcare provider if you have bone pain.
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Call your healthcare provider or go to the nearest hospital emergency room right away if you have any of the symptoms listed above. |
The most common side effects of VFEND in adults include: |
| - vision changes
- nausea
- hallucinations (seeing or hearing things that are not there)
| | - rash
- headache
- abnormal liver function tests
- chills
| | - vomiting
- fast heart beat (tachycardia)
- fever
|
The most common side effects of VFEND in children include: |
| - fever
- diarrhea
- low platelet counts
- abnormal liver function tests
- low blood calcium levels
- low blood phosphate levels
- vision changes
- rash
- stomach pain
| - high blood pressure
- cough
- low blood pressure
- swelling in the arms and legs
- high blood sugar levels
- headache
- fast heart beat (tachycardia)
- nose bleeds
- low blood potassium levels
| - inflammation of mucous membranes
- hallucinations (seeing or hearing things that are not there)
- coughing up blood
- constipation
- low blood magnesium levels
- fullness of the stomach area
- vomiting
- nausea
- upper respiratory tract infection
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Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of VFEND. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. |