TALZENNA What is the most important information I should know about TALZENNA?

(talazoparib)

What is the most important information I should know about TALZENNA?

TALZENNA may cause serious side effects, including:

Bone marrow problems called Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML). Some people who have cancer and who have received previous treatment with chemotherapy or certain other medicines for their cancer have developed MDS or AML during or after treatment with TALZENNA. MDS or AML may lead to death. If you develop MDS or AML, your healthcare provider will stop treatment with TALZENNA.

Symptoms of low blood cell counts are common during treatment with TALZENNA, but can be a sign of serious problems, including MDS or AML. Tell your healthcare provider if you have any of the following symptoms during treatment with TALZENNA:

•
weakness
•
weight loss
•
fever
•
frequent infections
•
blood in urine or stool
•
shortness of breath
•
feeling very tired
•
bruising or bleeding more easily

Your healthcare provider will do blood tests to check your blood cell counts:

•
every month during treatment with TALZENNA.
•
weekly if you have low blood cell counts that last a long time. Your healthcare provider may stop treatment with TALZENNA until your blood cell counts improve.

See "What are the possible side effects of TALZENNA?" below for other side effects of TALZENNA.

Find TALZENNA medical information:

Find TALZENNA medical information:

Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.

TALZENNA Quick Finder

Medication Guide

Health Professional Information

What is the most important information I should know about TALZENNA?

What is the most important information I should know about TALZENNA?

TALZENNA may cause serious side effects, including:

Bone marrow problems called Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML). Some people who have cancer and who have received previous treatment with chemotherapy or certain other medicines for their cancer have developed MDS or AML during or after treatment with TALZENNA. MDS or AML may lead to death. If you develop MDS or AML, your healthcare provider will stop treatment with TALZENNA.

Symptoms of low blood cell counts are common during treatment with TALZENNA, but can be a sign of serious problems, including MDS or AML. Tell your healthcare provider if you have any of the following symptoms during treatment with TALZENNA:

•
weakness
•
weight loss
•
fever
•
frequent infections
•
blood in urine or stool
•
shortness of breath
•
feeling very tired
•
bruising or bleeding more easily

Your healthcare provider will do blood tests to check your blood cell counts:

•
every month during treatment with TALZENNA.
•
weekly if you have low blood cell counts that last a long time. Your healthcare provider may stop treatment with TALZENNA until your blood cell counts improve.

See "What are the possible side effects of TALZENNA?" below for other side effects of TALZENNA.
Prescribing Information
Download Prescribing Information

Health Professional Information

What is the most important information I should know about TALZENNA?

What is the most important information I should know about TALZENNA?

TALZENNA may cause serious side effects, including:

Bone marrow problems called Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML). Some people who have cancer and who have received previous treatment with chemotherapy or certain other medicines for their cancer have developed MDS or AML during or after treatment with TALZENNA. MDS or AML may lead to death. If you develop MDS or AML, your healthcare provider will stop treatment with TALZENNA.

Symptoms of low blood cell counts are common during treatment with TALZENNA, but can be a sign of serious problems, including MDS or AML. Tell your healthcare provider if you have any of the following symptoms during treatment with TALZENNA:

•
weakness
•
weight loss
•
fever
•
frequent infections
•
blood in urine or stool
•
shortness of breath
•
feeling very tired
•
bruising or bleeding more easily

Your healthcare provider will do blood tests to check your blood cell counts:

•
every month during treatment with TALZENNA.
•
weekly if you have low blood cell counts that last a long time. Your healthcare provider may stop treatment with TALZENNA until your blood cell counts improve.

See "What are the possible side effects of TALZENNA?" below for other side effects of TALZENNA.

Resources

Didn’t find what you were looking for? Contact us.

MI Digital Assistant

Chat online with Pfizer Medical Information regarding your inquiry on a Pfizer medicine.

Call 800-438-1985*

*Contact Medical Information.9AM-5PM ET Monday to Friday; excluding holidays.

Report Adverse Event

Pfizer Safety

To report an adverse event related to the Pfizer-BioNTech COVID-19 Vaccine, and you are not part of a clinical trial* for this product, click the link below to submit your information:

Pfizer Safety Reporting Site

*If you are involved in a clinical trial for this product, adverse events should be reported to your coordinating study site.

If you cannot use the above website, or would like to report an adverse event related to a different Pfizer product, please call Pfizer Safety at (800) 438-1985.

FDA Medwatch

You may also contact the U.S. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns either online at www.fda.gov/medwatch or call (800) 822-7967.