PRISTIQ® What are the possible side effects of PRISTIQ?

(desvenlafaxine succinate)

What are the possible side effects of PRISTIQ?

•
See, "What is the most important information I should know about PRISTIQ?"
•
Serotonin syndrome. A potentially life-threatening problem called serotonin syndrome can happen when you take PRISTIQ with certain other medicines. See, "Do not take PRISTIQ if you:" Call your healthcare provider or go to the nearest hospital emergency room right away if you have any of the following signs and symptoms of serotonin syndrome:
o
agitation
o
confusion
o
fast heart beat
o
dizziness
o
flushing
o
tremors, stiff muscles, or muscle twitching
o
seizures
o
seeing or hearing things that are not real (hallucinations)
o
coma
o
changes in blood pressure
o
sweating
o
high body temperature (hyperthermia)
o
loss of coordination
o
nausea, vomiting, diarrhea
•
New or worsened high blood pressure (hypertension). Your healthcare provider should check your blood pressure before and during treatment with PRISTIQ. If you have high blood pressure, it should be controlled before you start treatment with PRISTIQ.
•
Increased chance of bleeding or bruising. Taking PRISTIQ with aspirin, NSAIDs, or blood thinners may add to this risk. Tell your healthcare provider right away about any unusual bleeding or bruising.
•
Eye problems (angle closure glaucoma). Many antidepressant medicines, including PRISTIQ, may cause a certain type of eye problem called angle-closure glaucoma. Call your healthcare provider if you have changes in your vision or eye pain.
•
Discontinuation syndrome. Suddenly stopping PRISTIQ when you take higher doses may cause you to have serious side effects. Your healthcare provider may want to decrease your dose slowly. Symptoms may include the following, some of which can be severe and last for a long time:
o
dizziness
o
irritability and agitation
o
anxiety
o
sweating
o
aggressiveness (including hostility, rage)
o
tremor
o
sweating
o
seizures
o
ringing in your ears (tinnitus)
o
nausea
o
problems sleeping
o
tiredness
o
confusion
o
electric shock sensation (paresthesia)
o
headache
o
diarrhea
o
abnormal dreams
o
changes in your mood
o
hypomania
o
problems with eyesight (such as blurred vision and trouble focusing)
o
increase in blood pressure
•
Seizures (convulsions).
•
Low sodium levels in your blood (hyponatremia). Low sodium levels can happen during treatment with PRISTIQ. Low sodium levels in your blood may be serious and may cause death. Signs and Symptoms of low sodium levels in your blood may include:
•
headache
•
difficulty concentrating
•
memory changes
•
confusion
•
weakness and unsteadiness on your feet which can lead to falls
 
In severe or more sudden cases, signs and symptoms include:
•
hallucinations (seeing or hearing things that are not real)
•
fainting
•
seizures
•
coma
•
Lung problems. Some people who have taken the medicine venlafaxine which is the same kind of medicine as the medicine in PRISTIQ have had lung problems. Symptoms of lung problems include difficulty breathing, cough, or chest discomfort. Tell your healthcare provider right away if you have any of these symptoms.
•
Sexual Problems (dysfunction). Taking serotonin and norepinephrine reuptake inhibitors (SNRIs), including PRISTIQ, may cause sexual problems.
Symptoms in males may include:
o
Delayed ejaculation or inability to have an ejaculation
o
Decreased sex drive
o
Problems getting or keeping an erection
 
Symptoms in females may include:
o
Decreased sex drive
o
Delayed orgasm or inability to have an orgasm
 
Talk to your healthcare provider if you develop any changes in your sexual function or if you have any questions or concerns about sexual problems during treatment with PRISTIQ. There may be treatments your healthcare provider can suggest.

The most common side effects of PRISTIQ include:

•
nausea
•
problems sleeping
•
constipation
•
decreased appetite
•
sexual function problems
•
dizziness
•
sweating
•
feeling sleepy
•
anxiety

These are not all the possible side effects of PRISTIQ.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Health Professional Information

What are the possible side effects of PRISTIQ?

What are the possible side effects of PRISTIQ?

•
See, "What is the most important information I should know about PRISTIQ?"
•
Serotonin syndrome. A potentially life-threatening problem called serotonin syndrome can happen when you take PRISTIQ with certain other medicines. See, "Do not take PRISTIQ if you:" Call your healthcare provider or go to the nearest hospital emergency room right away if you have any of the following signs and symptoms of serotonin syndrome:
o
agitation
o
confusion
o
fast heart beat
o
dizziness
o
flushing
o
tremors, stiff muscles, or muscle twitching
o
seizures
o
seeing or hearing things that are not real (hallucinations)
o
coma
o
changes in blood pressure
o
sweating
o
high body temperature (hyperthermia)
o
loss of coordination
o
nausea, vomiting, diarrhea
•
New or worsened high blood pressure (hypertension). Your healthcare provider should check your blood pressure before and during treatment with PRISTIQ. If you have high blood pressure, it should be controlled before you start treatment with PRISTIQ.
•
Increased chance of bleeding or bruising. Taking PRISTIQ with aspirin, NSAIDs, or blood thinners may add to this risk. Tell your healthcare provider right away about any unusual bleeding or bruising.
•
Eye problems (angle closure glaucoma). Many antidepressant medicines, including PRISTIQ, may cause a certain type of eye problem called angle-closure glaucoma. Call your healthcare provider if you have changes in your vision or eye pain.
•
Discontinuation syndrome. Suddenly stopping PRISTIQ when you take higher doses may cause you to have serious side effects. Your healthcare provider may want to decrease your dose slowly. Symptoms may include the following, some of which can be severe and last for a long time:
o
dizziness
o
irritability and agitation
o
anxiety
o
sweating
o
aggressiveness (including hostility, rage)
o
tremor
o
sweating
o
seizures
o
ringing in your ears (tinnitus)
o
nausea
o
problems sleeping
o
tiredness
o
confusion
o
electric shock sensation (paresthesia)
o
headache
o
diarrhea
o
abnormal dreams
o
changes in your mood
o
hypomania
o
problems with eyesight (such as blurred vision and trouble focusing)
o
increase in blood pressure
•
Seizures (convulsions).
•
Low sodium levels in your blood (hyponatremia). Low sodium levels can happen during treatment with PRISTIQ. Low sodium levels in your blood may be serious and may cause death. Signs and Symptoms of low sodium levels in your blood may include:
•
headache
•
difficulty concentrating
•
memory changes
•
confusion
•
weakness and unsteadiness on your feet which can lead to falls
 
In severe or more sudden cases, signs and symptoms include:
•
hallucinations (seeing or hearing things that are not real)
•
fainting
•
seizures
•
coma
•
Lung problems. Some people who have taken the medicine venlafaxine which is the same kind of medicine as the medicine in PRISTIQ have had lung problems. Symptoms of lung problems include difficulty breathing, cough, or chest discomfort. Tell your healthcare provider right away if you have any of these symptoms.
•
Sexual Problems (dysfunction). Taking serotonin and norepinephrine reuptake inhibitors (SNRIs), including PRISTIQ, may cause sexual problems.
Symptoms in males may include:
o
Delayed ejaculation or inability to have an ejaculation
o
Decreased sex drive
o
Problems getting or keeping an erection
 
Symptoms in females may include:
o
Decreased sex drive
o
Delayed orgasm or inability to have an orgasm
 
Talk to your healthcare provider if you develop any changes in your sexual function or if you have any questions or concerns about sexual problems during treatment with PRISTIQ. There may be treatments your healthcare provider can suggest.

The most common side effects of PRISTIQ include:

•
nausea
•
problems sleeping
•
constipation
•
decreased appetite
•
sexual function problems
•
dizziness
•
sweating
•
feeling sleepy
•
anxiety

These are not all the possible side effects of PRISTIQ.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Prescribing Information
Download Prescribing Information

Health Professional Information

What are the possible side effects of PRISTIQ?

What are the possible side effects of PRISTIQ?

•
See, "What is the most important information I should know about PRISTIQ?"
•
Serotonin syndrome. A potentially life-threatening problem called serotonin syndrome can happen when you take PRISTIQ with certain other medicines. See, "Do not take PRISTIQ if you:" Call your healthcare provider or go to the nearest hospital emergency room right away if you have any of the following signs and symptoms of serotonin syndrome:
o
agitation
o
confusion
o
fast heart beat
o
dizziness
o
flushing
o
tremors, stiff muscles, or muscle twitching
o
seizures
o
seeing or hearing things that are not real (hallucinations)
o
coma
o
changes in blood pressure
o
sweating
o
high body temperature (hyperthermia)
o
loss of coordination
o
nausea, vomiting, diarrhea
•
New or worsened high blood pressure (hypertension). Your healthcare provider should check your blood pressure before and during treatment with PRISTIQ. If you have high blood pressure, it should be controlled before you start treatment with PRISTIQ.
•
Increased chance of bleeding or bruising. Taking PRISTIQ with aspirin, NSAIDs, or blood thinners may add to this risk. Tell your healthcare provider right away about any unusual bleeding or bruising.
•
Eye problems (angle closure glaucoma). Many antidepressant medicines, including PRISTIQ, may cause a certain type of eye problem called angle-closure glaucoma. Call your healthcare provider if you have changes in your vision or eye pain.
•
Discontinuation syndrome. Suddenly stopping PRISTIQ when you take higher doses may cause you to have serious side effects. Your healthcare provider may want to decrease your dose slowly. Symptoms may include the following, some of which can be severe and last for a long time:
o
dizziness
o
irritability and agitation
o
anxiety
o
sweating
o
aggressiveness (including hostility, rage)
o
tremor
o
sweating
o
seizures
o
ringing in your ears (tinnitus)
o
nausea
o
problems sleeping
o
tiredness
o
confusion
o
electric shock sensation (paresthesia)
o
headache
o
diarrhea
o
abnormal dreams
o
changes in your mood
o
hypomania
o
problems with eyesight (such as blurred vision and trouble focusing)
o
increase in blood pressure
•
Seizures (convulsions).
•
Low sodium levels in your blood (hyponatremia). Low sodium levels can happen during treatment with PRISTIQ. Low sodium levels in your blood may be serious and may cause death. Signs and Symptoms of low sodium levels in your blood may include:
•
headache
•
difficulty concentrating
•
memory changes
•
confusion
•
weakness and unsteadiness on your feet which can lead to falls
 
In severe or more sudden cases, signs and symptoms include:
•
hallucinations (seeing or hearing things that are not real)
•
fainting
•
seizures
•
coma
•
Lung problems. Some people who have taken the medicine venlafaxine which is the same kind of medicine as the medicine in PRISTIQ have had lung problems. Symptoms of lung problems include difficulty breathing, cough, or chest discomfort. Tell your healthcare provider right away if you have any of these symptoms.
•
Sexual Problems (dysfunction). Taking serotonin and norepinephrine reuptake inhibitors (SNRIs), including PRISTIQ, may cause sexual problems.
Symptoms in males may include:
o
Delayed ejaculation or inability to have an ejaculation
o
Decreased sex drive
o
Problems getting or keeping an erection
 
Symptoms in females may include:
o
Decreased sex drive
o
Delayed orgasm or inability to have an orgasm
 
Talk to your healthcare provider if you develop any changes in your sexual function or if you have any questions or concerns about sexual problems during treatment with PRISTIQ. There may be treatments your healthcare provider can suggest.

The most common side effects of PRISTIQ include:

•
nausea
•
problems sleeping
•
constipation
•
decreased appetite
•
sexual function problems
•
dizziness
•
sweating
•
feeling sleepy
•
anxiety

These are not all the possible side effects of PRISTIQ.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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