INDICATIONS AND USAGE
Zarontin is indicated for the control of absence (petit mal) epilepsy.
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ZARONTIN® Oral Solution (ethosuximide)
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Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.
ZARONTIN® Oral Solution Quick Finder
Dosage and Administration
DOSAGE AND ADMINISTRATION
Zarontin is administered by the oral route. The initial dose for patients 3 to 6 years of age is one teaspoonful (250 mg) per day; for patients 6 years of age and older...
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Contraindications
CONTRAINDICATIONS
Ethosuximide should not be used in patients with a history of hypersensitivity to succinimides.
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Warnings and Precautions
WARNINGS
Blood Dyscrasias
Blood dyscrasias, including some with fatal outcome, have been reported to be associated with the use of ethosuximide; therefore, periodic...
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Adverse Reactions
ADVERSE REACTIONS
Body As A Whole: Allergic reaction, Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS).
Gastrointestinal System: Gastrointestinal symptoms...
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Overdosage
OVERDOSAGE
Acute overdoses may produce nausea, vomiting, and CNS depression including coma with respiratory depression. A relationship between ethosuximide toxicity and its plasma levels has not been established. The...
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Description
DESCRIPTION
Zarontin (ethosuximide) is an anticonvulsant succinimide, chemically designated as alpha-ethyl-alpha-methyl-succinimide, with the following structural formula:
...
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Clinical Pharmacology
CLINICAL PHARMACOLOGY
Ethosuximide suppresses the paroxysmal three cycle per second spike and wave activity associated with lapses of consciousness which is common in absence (petit mal) seizures. The frequency of...
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How Supplied/Storage and Handling
HOW SUPPLIED
Zarontin is supplied as:
NDC 0071-2418-35: 1 pint amber polyethylene terephthalate (PET) bottles (polyvinyl cap liner).
NDC 0071-2418-19: 1 pint amber polyethylene...
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Medication Guide
MEDICATION GUIDE
ZARONTIN, (Ză rŏn' tĭn)
(ethosuximide)
Capsules, Oral Solution
Read this Medication Guide before you start taking ZARONTIN and each time...
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Report Adverse Event
To report an adverse event related to Pfizer-BioNTech COVID-19 Vaccine (also known as COMIRNATY®, COVID-19 mRNA, Vaccine BNT162b2 or BNT162) or Pfizer COVID-19 Treatment (also known as PAXLOVID™ (nirmatrelvir tablets; ritonavir tablets)), and you are not part of a clinical trial* for this product, click the link below to submit your information:
*If you are involved in a clinical trial for either product, adverse events should be reported to your coordinating study site.
If you cannot use the above website or would like to report an adverse event related to a different Pfizer product, please call Pfizer Safety at(800) 438-1985.
You may also contact the U.S. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns either online at www.fda.gov/medwatchor by calling
(800)-332-1088.
(800)-332-1088.