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verapamil hydrochloride injection, USP

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verapamil hydrochloride injection, USP Quick Finder

INDICATIONS AND USAGE

Verapamil Hydrochloride Injection, USP is indicated for the following:

• Rapid conversion to sinus rhythm of paroxysmal supraventricular tachycardias, including those associated with accessory...

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DOSAGE AND ADMINISTRATION

FOR INTRAVENOUS USE ONLY. VERAPAMIL HYDROCHLORIDE INJECTION SHOULD BE GIVEN AS A SLOW INTRAVENOUS INJECTION OVER AT LEAST A TWO-MINUTE PERIOD OF TIME UNDER...

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CONTRAINDICATIONS

Verapamil hydrochloride injection is contraindicated in:

1. Severe hypotension or cardiogenic shock.

2. Second- or third-degree AV block (except in patients with a functioning artificial...

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WARNINGS

VERAPAMIL HYDROCHLORIDE SHOULD BE GIVEN AS A SLOW INTRAVENOUS INJECTION OVER AT LEAST A TWO-MINUTE PERIOD OF TIME (see DOSAGE AND ADMINISTRATION...

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ADVERSE REACTIONS

The following reactions were reported with verapamil hydrochloride injection used in controlled U.S. clinical trials involving 324 patients:

Cardiovascular:...

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OVERDOSAGE

Treatment of overdosage should be supportive and individualized. Beta-adrenergic stimulation and/or parenteral administration of calcium injections may increase calcium ion flux across the slow channel, and have...

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DESCRIPTION

Verapamil hydrochloride is a calcium antagonist or slow-channel inhibitor. Verapamil Hydrochloride Injection, USP is a sterile, nonpyrogenic solution containing verapamil hydrochloride 2.5 mg/mL and sodium...

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CLINICAL PHARMACOLOGY

Mechanism of Action: Verapamil inhibits the calcium ion (and possibly sodium ion) influx through slow channels into conductile and contractile...

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HOW SUPPLIED

Verapamil Hydrochloride Injection, USP 2.5 mg/mL is supplied in single-dose containers as follows:

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Ansyr™ Plastic Syringe

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