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TPN ELECTROLYTES Description (multitple electrolyte additive)

DESCRIPTION

TPN Electrolytes (multiple electrolyte additive) is a sterile, nonpyrogenic, concentrated solution of intra- and extracellular ions for intravenous infusion after dilution as a maintenance electrolyte replenisher only. It contains no phosphate and no bacteriostat, antimicrobial agent or added buffer. The pH is 6.6 (6.0 to 7.5). May contain hydrochloric acid for pH adjustment. The osmolar concentration is 6.2 mOsmol/mL (calc.).

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*Total Parenteral Nutrition

Ingredients and ion constituents of the solution are as follows:

Ingredient or Ion

mg/20 mL

mEq/20 mL

Sodium Chloride

321

Calcium Chloride (dihydrate)

331

Potassium Chloride

1491

Magnesium Chloride (hexahydrate)

508

Sodium Acetate (anhydrous)

2420

Sodium (Na+)

35

Potassium (K+)

20

Calcium (Ca++)

4.5

Magnesium (Mg++)

5

Chloride (Cl)

35

Acetate (CH3COO)

29.5

Sodium Chloride, USP is chemically designated NaCl, a white crystalline compound freely soluble in water.

Calcium Chloride, USP dihydrate is chemically designated CaCl2 • 2H2O, white, odorless fragments or granules, freely soluble in water.

Potassium Chloride, USP is chemically designated KCl, a white granular powder freely soluble in water.

Magnesium Chloride, USP hexahydrate is chemically designated MgCl2 • 6H2O, deliquescent crystals very soluble in water.

Sodium Acetate, USP anhydrous is chemically designated C2H3NaO2, a hygroscopic powder very soluble in water.

Water for Injection, USP is chemically designated H2O.

The semi-rigid container is fabricated from a specially formulated polyolefin. It is a copolymer of ethylene and propylene. The safety of the plastic has been confirmed by tests in animals according to USP biological standards for plastic containers. The container requires no vapor barrier to maintain the proper drug concentration.

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