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tobramycin injection, USP

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tobramycin injection, USP Quick Finder

WARNINGS

Patients treated with Tobramycin Injection, USP and other aminoglycosides should be under close clinical observation, because these drugs have an inherent potential for causing...

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INDICATIONS AND USAGE

To reduce the development of drug-resistant bacteria and maintain the effectiveness of tobramycin and other antibacterial drugs, tobramycin should be used only to treat or prevent infections that are...

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DOSAGE AND ADMINISTRATION

Tobramycin Injection, USP may be given intramuscularly or intravenously. Recommended dosages are the same for both routes. The patient's pretreatment body weight should be obtained for calculation...

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CONTRAINDICATIONS

A hypersensitivity to any aminoglycoside is a contraindication to the use of tobramycin. A history of hypersensitivity or serious toxic reactions to aminoglycosides may also contraindicate the use of any...

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WARNINGS

See WARNINGS box above.

Tobramycin Injection, USP contains sodium metabisulfite, a sulfite that may cause allergic-type reactions, including anaphylactic...

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ADVERSE REACTIONS

Neurotoxicity: Adverse effects on both the vestibular and auditory branches of the eighth nerve have been noted, especially in patients receiving high...

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OVERDOSAGE

Signs and Symptoms: The severity of the signs and symptoms following a tobramycin overdose are dependent on the dose administered, the patient's renal...

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DESCRIPTION

Tobramycin Sulfate, a water-soluble antibiotic of the aminoglycoside group, is derived from the actinomycete Streptomyces tenebrarius. Tobramycin...

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CLINICAL PHARMACOLOGY

Tobramycin is rapidly absorbed following intramuscular administration. Peak serum concentrations of tobramycin occur between 30 and 90 minutes after intramuscular administration.

Following an...

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HOW SUPPLIED

Tobramycin Injection, USP is available as:

...
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Injection, USP
Multiple Dose
Fliptop Vial

Rx only

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