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TICOVAC Dosage and Administration (tick-borne encephalitis vaccine,whole virus, inactivated)


For intramuscular use only.

2.1 Dosage and Vaccination Schedule

  • 1 through 15 years of age: each dose 0.25 mL
  • 16 years of age and older: each dose 0.5 mL

Primary Vaccination: Three doses

Table 1: Primary Vaccination Schedule - TICOVAC
1 through 15 years of age16 years of age and older
First doseDay 0Day 0
Second dose1 to 3 months after the first vaccination14 days to 3 months after the first vaccination
Third dose5 to 12 months after the second vaccination5 to 12 months after the second vaccination

Complete the primary immunization series at least 1 week prior to potential exposure to TBEV (tick-borne encephalitis virus) [see Clinical Studies (14.1)].

A booster dose (fourth dose) may be given at least 3 years after completion of the primary immunization series if ongoing exposure or re-exposure to TBEV is expected.

2.2 Administration

Bring the vaccine to room temperature before administration. Shake well prior to administration to thoroughly mix the vaccine suspension. After shaking, the vaccine should be a homogenous off-white, opalescent suspension. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Do not administer if particulate matter or discoloration remains after shaking. Administer vaccine by intramuscular injection.

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