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SYNERCID®(quinupristin, dalfopristin)

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Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.

SYNERCID® Quick Finder

INDICATIONS AND USAGE

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Synercid and other antibacterial drugs, Synercid should be used...

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DOSAGE AND ADMINISTRATION

Synercid should be administered by intravenous infusion in 5% Dextrose in Water solution over a 60-minute period. (See

Special Populations

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CONTRAINDICATIONS

Synercid is contraindicated in patients with known hypersensitivity to Synercid, or with prior hypersensitivity to other streptogramins (...

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WARNINGS

Drug Interactions

In vitro drug interaction studies have demonstrated that Synercid significantly...

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ADVERSE REACTIONS

The safety of Synercid was evaluated in 1099 patients enrolled in 5 comparative clinical trials. Additionally, 4 non-comparative clinical trials (3 prospective and 1 retrospective...

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OVERDOSAGE

There are four reports of patients receiving Synercid doses at up to three times that recommended (7.5 mg/kg). No adverse events were considered possibly or probably related to...

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DESCRIPTION

Synercid® (quinupristin and dalfopristin powder for injection) I.V., a streptogramin antibacterial agent for intravenous administration, is a sterile lyophilized...

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CLINICAL PHARMACOLOGY

Pharmacokinetics

Quinupristin and dalfopristin are the main active components circulating in plasma in human subjects. Quinupristin and...

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CLINICAL STUDIES

COMPARATIVE TRIALS

Complicated Skin and Skin Structure Infections

Two randomized, open-label...

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HOW SUPPLIED

Synercid is supplied as a sterile lyophilized pyrogen-free preparation in single-dose 10 mL type I glass vials with gray elastomeric closure, and aluminum seal with a dark blue flip-off...

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To reduce the development of drug-resistant bacteria and maintain the effectiveness of Synercid and other antibacterial drugs, ...

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