Medical Information
United States
 

In order to provide you with relevant and meaningful content we need to know more about you.

Please choose the category that best describes you.

This content is intended for U.S. Healthcare Professionals. Would you like to proceed?

If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.

Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.
Not a healthcare professional? Go to the patient or caregiver website.

R-GENE® 10 (arginine HCl)

If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.

Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.

R-GENE® 10 Quick Finder

INDICATIONS AND USAGE

R-Gene® 10 is indicated as an intravenous stimulant to the pituitary for the release of human growth hormone in patients where the measurement of pituitary reserve for HGH can...

Did you find an answer to your question? Yes No

DOSAGE AND ADMINISTRATION

Adult Dosage

The recommended adult dose is 30 g arginine hydrochloride (300 mL of R-Gene® 10) administered by...

Did you find an answer to your question? Yes No

CONTRAINDICATIONS

The administration of R-Gene® 10 is contraindicated in persons having known hypersensitivity to any ingredient in this product.

Did you find an answer to your question? Yes No

WARNINGS

There have been reports of overdosage of R-Gene® 10 in pediatric patients leading to death. EXTREME CAUTION MUST BE EXERCISED WHEN INFUSING R-GENE® 10 INTO PEDIATRIC...

Did you find an answer to your question? Yes No

ADVERSE REACTIONS

Adverse reactions associated with 1670 infusions in premarketing studies were as follows:

Non-specific side effects consisting of nausea, vomiting, headache, flushing, numbness and local venous...

Did you find an answer to your question? Yes No

OVERDOSAGE

An overdosage may cause a transient metabolic acidosis with hyperventilation, which could lead to death (see "WARNINGS"). In most cases the acidosis will self-compensate and the base...

Did you find an answer to your question? Yes No

DESCRIPTION

Each 100 mL of R-Gene® 10 (Arginine Hydrochloride Injection, USP) for intravenous use contains 10 g of L-Arginine Hydrochloride, USP in Water for Injection, USP (equivalent to a 10%...

Did you find an answer to your question? Yes No

CLINICAL PHARMACOLOGY

Intravenous infusion of R-Gene® 10 often induces a pronounced rise in the plasma level of human growth hormone (HGH) in subjects with intact pituitary function. This rise is...

Did you find an answer to your question? Yes No

HOW SUPPLIED

R-Gene® 10 is supplied as a 30 g/300 mL (0.1 g/mL) fill in 500 mL glass containers.

Preservative Free: Discard any unused portion.

NDC 0009-0436-01...

Did you find an answer to your question? Yes No
Did you find an answer to your question? Yes No
Didn’t find what you were looking for? Contact us.
Report Adverse Event