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QUELICIN® (succinylcholine chloride injection, USP)

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Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.

QUELICIN® Quick Finder

HIGHLIGHTS OF PRESCRIBING INFORMATION

These highlights do not include all the...
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WARNING: VENTRICULAR DYSRHYTHMIAS, CARDIAC ARREST, AND DEATH FROM HYPERKALEMIC RHABDOMYOLYSIS IN PEDIATRIC PATIENTS

Acute rhabdomyolysis with hyperkalemia followed by ventricular dysrhythmias, cardiac arrest, and death has occurred...
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1 INDICATIONS AND USAGE

QUELICIN is indicated in adults and pediatric patients:

as an adjunct to general anesthesia
to facilitate tracheal intubation
to provide...
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2 DOSAGE AND ADMINISTRATION

2.1 Important Dosage and Administration Information

QUELICIN is for intravenous or intramuscular use only.
QUELICIN...
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3 DOSAGE FORMS AND STRENGTHS

QUELICIN™ (Succinylcholine Chloride Injection, USP) is supplied as a clear, colorless solution as follows:

1,000 mg/10 mL (100 mg/mL) in single-dose fliptop vials contains:...
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5 WARNINGS AND PRECAUTIONS

5.1 Ventricular Dysrhythmias, Cardiac Arrest, and Death From Hyperkalemic Rhabdomyolysis in Pediatric Patients

There have been reports of...

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6 ADVERSE REACTIONS

The following clinically significant adverse reactions are discussed in greater detail in other sections of the labeling:

Ventricular Dysrhythmias, Cardiac Arrest, and Death from...
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7 DRUG INTERACTIONS

7.1 Drugs that May Affect the Neuromuscular Blocking Action of QUELICIN

Drugs that may enhance the neuromuscular blocking action of...

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8 USE IN SPECIFIC POPULATIONS

8.1 Pregnancy

Risk Summary

Available data from...

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10 OVERDOSAGE

Overdosage with QUELICIN may result in neuromuscular block beyond the time needed for surgery and anesthesia. This may be manifested by skeletal muscle weakness, decreased respiratory reserve, low tidal volume...

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11 DESCRIPTION

QUELICIN (Succinylcholine Chloride Injection, USP) is a sterile, nonpyrogenic solution to be used as a short-acting, depolarizing neuromuscular blocker for intravenous or intramuscular use. QUELICIN contains...

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12 CLINICAL PHARMACOLOGY

12.1 Mechanism of Action

Succinylcholine is a depolarizing neuromuscular blocker. As does acetylcholine, it combines with the cholinergic...

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13 NONCLINICAL TOXICOLOGY

13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility

...

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16 HOW SUPPLIED/STORAGE AND HANDLING

QUELICIN (Succinylcholine Chloride Injection, USP) is supplied as a clear, colorless solution in the following concentrations and packages:

...
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Distributed by Hospira, Inc., Lake Forest, IL 60045 USA

LAB-1246-6.0

...
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