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propofol injectable emulsion How Supplied/Storage and Handling


Propofol Injectable Emulsion, USP is supplied as follows:

Unit of SaleConcentration
NDC 0409-4699-30
Carton of 5 Single patient use Fliptop vials
200 mg/20 mL
(10 mg/mL)
NDC 0409-4699-33
Tray of 20 Single patient use Fliptop vials
500 mg/50 mL
(10 mg/mL)
NDC 0409-4699-24
Tray of 10 Single patient use Fliptop vials
1 g/100 mL
(10 mg/mL)

Propofol undergoes oxidative degradation, in the presence of oxygen, and is therefore packaged under nitrogen to eliminate this degradation path.

Store at 20 to 25°C (68 to 77°F). [See USP Controlled Room Temperature]. Do not freeze. Shake well before use. Do not use if there is evidence of excessive creaming or aggregation, if large droplets are visible, or if there are other forms of phase separation indicating that the stability of the product has been compromised. Slight creaming, which should disappear after shaking, may be visible upon prolonged standing.

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