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propofol injectable emulsion (contains benzyl alcohol)

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propofol injectable emulsion (contains benzyl alcohol) Quick Finder

INDICATIONS AND USAGE

Propofol injectable emulsion is an IV general anesthetic and sedation drug that can be used as described in the table below.

TABLE 3. INDICATIONS FOR PROPOFOL...
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DOSAGE AND ADMINISTRATION

NOTE: CONTAINS BENZYL ALCOHOL (see

Induction of General Anesthesia

Adult Patients

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CONTRAINDICATIONS

Propofol injectable emulsion is contraindicated in patients with a known hypersensitivity to propofol injectable emulsion or any of its components.

Propofol injectable emulsion is contraindicated in...

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WARNINGS

Use of propofol injectable emulsion has been associated with both fatal and life-threatening anaphylactic and anaphylactoid reactions.

For general anesthesia or monitored anesthesia care (MAC) sedation,...

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ADVERSE REACTIONS

To report SUSPECTED ADVERSE REACTIONS, contact Hospira, Inc. at 1-800-441-4100 or FDA at 1-800-FDA-1088 or www.fda.gov.

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DRUG ABUSE AND DEPENDENCE

There are reports of the abuse of propofol for recreational and other improper purposes, which have resulted in fatalities and other injuries. Instances of self-administration of propofol injectable...

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OVERDOSAGE

If overdosage occurs, propofol injectable emulsion administration should be discontinued immediately. Overdosage is likely to cause cardiorespiratory depression. Respiratory depression should be treated by...

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DESCRIPTION

Propofol Injectable Emulsion, USP is a sterile, nonpyrogenic emulsion containing 10 mg/mL of propofol suitable for intravenous administration. Propofol is chemically described as 2,6-diisopropylphenol. The...

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CLINICAL PHARMACOLOGY

General

Propofol is an intravenous general anesthetic and sedation drug for use in the induction and maintenance of anesthesia or sedation....

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ANIMAL TOXICOLOGY AND/OR PHARMACOLOGY

Published studies in animals demonstrate that the use of anesthetic agents during the period of rapid brain growth or synaptogenesis results in widespread neuronal and oligodendrocyte...

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HOW SUPPLIED

Propofol Injectable Emulsion, USP is supplied as follows:

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Rx only

CONTAINS BENZYL ALCOHOL (see

Distributed by Hospira, Inc., Lake Forest, IL 60045 USA
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