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PROCARDIA® XL (nifedipine extended release tablets)

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Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.

PROCARDIA® XL Quick Finder

INDICATIONS AND USAGE

I. Vasospastic Angina

PROCARDIA XL is indicated for the management of vasospastic angina confirmed by any of the following criteria: 1) classical...

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DOSAGE AND ADMINISTRATION

Dosage must be adjusted according to each patient's needs. Therapy for either hypertension or angina should be initiated with 30 or 60 mg once daily. PROCARDIA XL Extended Release Tablets should be...

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CONTRAINDICATIONS

Known hypersensitivity reaction to nifedipine.

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WARNINGS

Excessive Hypotension

Although in most angina patients the hypotensive effect of nifedipine is modest and well tolerated, occasional patients have had...

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ADVERSE EXPERIENCES

Over 1000 patients from both controlled and open trials with PROCARDIA XL Extended Release Tablets in hypertension and angina were included in the evaluation of adverse experiences. All side effects...

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OVERDOSAGE

Experience with nifedipine overdosage is limited. Generally, overdosage with nifedipine leading to pronounced hypotension calls for active cardiovascular support, including monitoring of cardiovascular and...

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DESCRIPTION

Nifedipine is a drug belonging to a class of pharmacological agents known as the calcium channel blockers. Nifedipine is 3,5-pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, dimethyl ester,...

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CLINICAL PHARMACOLOGY

Nifedipine is a calcium ion influx inhibitor (slow-channel blocker or calcium ion antagonist) and inhibits the transmembrane influx of calcium ions into cardiac muscle and smooth muscle. The contractile...

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HOW SUPPLIED

PROCARDIA XL Extended Release Tablets are supplied to provide 30 mg, 60 mg and 90 mg round, biconvex, rose-pink, film-coated tablets in:

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LAB-0176-12.0
Revised May 2021

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