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PREMARIN® INTRAVENOUS How Supplied/Storage and Handling (conjugated estrogens)

HOW SUPPLIED

NDC 0046-0749-05–Each package provides one SECULE vial containing 25 mg of conjugated estrogens, USP, for injection (also lactose 200 mg, sodium citrate 12.2 mg, and simethicone 0.2 mg). The pH is adjusted with sodium hydroxide or hydrochloric acid.

Premarin Intravenous (conjugated estrogens, USP) for injection is prepared by cryodesiccation.

SECULE-Registered trademark to designate a vial containing an injectable preparation in dry form.


DIRECTIONS FOR STORAGE AND RECONSTITUTION

STORAGE BEFORE RECONSTITUTION

Store package in refrigerator, 2° to 8°C (36° to 46°F).

TO RECONSTITUTE

Reconstitute Premarin Intravenous with 5 mL of Sterile Water for Injection, USP. Introduce the sterile diluent slowly against the side of SECULE vial and agitate gently. Do not shake violently. Use immediately after reconstitution.

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