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potassium chloride for injection concentrate, USP Overdosage

OVERDOSAGE

In the event of fluid overload during parenteral therapy, re-evaluate the patient's condition, and institute appropriate corrective treatment.

In the event of overdosage with potassium-containing solutions, discontinue the infusion immediately, and institute corrective therapy to reduce serum potassium levels.

Treatment of hyperkalemia includes the following:

1.
Dextrose Injection USP, 10% or 25%, containing 10 units of crystalline insulin per 20 grams of dextrose administered intravenously, at a rate of 300 to 500 mL per hour.
2.
Absorption and exchange of potassium using sodium or ammonium cycle cation exchange resin, orally and as retention enema.
3.
Hemodialysis and peritoneal dialysis. The use of potassium-containing foods or medications must be eliminated. However, in cases of digitalization, too rapid a lowering of plasma potassium concentration can cause digitalis toxicity.
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