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potassium chloride for injection concentrate, USP Description

DESCRIPTION

Potassium Chloride for Injection Concentrate, USP, is a sterile, nonpyrogenic, concentrated solution of potassium chloride, USP in water for injection administered by intravenous infusion only after dilution in a larger volume of fluid. They are provided in the following variety of concentrations and sizes comprising a choice of single-dose containers, all designed to provide the commonly prescribed amounts of potassium chloride for single-dose infusion after dilution in suitable large volume parenterals.

*
May contain hydrochloric acid for pH adjustment.

Additive Solution*

(conc. & size)

K+

mEq/mL

KCl

mg/mL

mOsmol/mL

(calc.)

10 mEq/5 mL

2

149

4

20 mEq/10 mL

2

149

4

30 mEq/15 mL

2

149

4

40 mEq/20 mL

2

149

4

The solutions contain no bacteriostat, antimicrobial agent or added buffer (except for pH adjustment) and each is intended only for single-dose injection (after dilution). When smaller doses are required, discard the unused portion. The pH is 4.6 (4.0 to 8.0).

Potassium Chloride for Injection Concentrate, USP (appropriately diluted) is a parenteral fluid and electrolyte replenisher.

Potassium Chloride, USP is chemically designated KCl, a white granular powder freely soluble in water.

The semi-rigid material used for the plastic vials is fabricated from a specially formulated polyolefin. It is a copolymer of ethylene and propylene. The safety of the plastic has been confirmed by tests in animals according to USP biological standards for plastic containers. The container requires no vapor barrier to maintain the proper drug concentration.

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