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piperacillin tazobactam for injection - VIAL
If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.
Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.
piperacillin tazobactam for injection - VIAL Quick Finder
Highlights
Indications and Usage
1 INDICATIONS AND USAGE
1.1 Intra-abdominal Infections
Piperacillin and tazobactam for injection is indicated in adults and pediatric patients (2 months of age and...
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Dosage and Administration
2 DOSAGE AND ADMINISTRATION
2.2 Dosage in Adult Patients with Indications Other Than Nosocomial Pneumonia
The usual total daily dosage of piperacillin and tazobactam...
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Dosage Forms and Strengths
3 DOSAGE FORMS AND STRENGTHS
Piperacillin and tazobactam for injection, USP is supplied as a white to yellowish powder in vials of the following sizes:
Each piperacillin and tazobactam for injection, USP 2.25 g vial...
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Contraindications
4 CONTRAINDICATIONS
Piperacillin and tazobactam for injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or beta-lactamase inhibitors.
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Warnings and Precautions
5 WARNINGS AND PRECAUTIONS
5.1 Hypersensitivity Adverse Reactions
Serious and occasionally fatal hypersensitivity (anaphylactic/anaphylactoid) reactions (including...
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Adverse Reactions
6 ADVERSE REACTIONS
6.1 Clinical Trials Experience
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the...
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Drug Interactions
7 DRUG INTERACTIONS
7.1 Aminoglycosides
Piperacillin may inactivate aminoglycosides by converting them to microbiologically inert amides.
...
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Use in Specific Populations
8 USE IN SPECIFIC POPULATIONS
8.1 Pregnancy
Risk Summary
Piperacillin and tazobactam cross the placenta...
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Overdosage
10 OVERDOSAGE
There have been post-marketing reports of overdose with piperacillin/tazobactam. The majority of those events experienced, including nausea, vomiting, and diarrhea, have also been reported with the usual...
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Description
11 DESCRIPTION
Piperacillin and tazobactam for injection, USP is an injectable antibacterial combination products consisting of the semisynthetic antibacterial piperacillin sodium and the beta-lactamase inhibitor tazobactam...
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Clinical Pharmacology
12 CLINICAL PHARMACOLOGY
12.1 Mechanism of Action
Piperacillin and tazobactam for injection is an antibacterial drug [...
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Nonclinical Toxicology
13 NONCLINICAL TOXICOLOGY
13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility
Carcinogenesis
Long-...
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References
15 REFERENCES
- 1.
- Jensen J-US, Hein L, Lundgren B, et al. BMJ Open 2012; 2:e000635. doi:10.1136.
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How Supplied/Storage and Handling
16 HOW SUPPLIED/STORAGE AND HANDLING
Piperacillin and tazobactam for injection, USP is supplied as single-dose vials in the following sizes:
Each piperacillin and tazobactam for injection, USP 2.25 g vial provides...
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Medication Guide
17 PATIENT COUNSELING INFORMATION
Serious Hypersensitivity Reactions
Advise patients, their families, or caregivers that serious hypersensitivity reactions, including serious allergic...
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Report Adverse Event
To report an adverse event related to Pfizer-BioNTech COVID-19 Vaccine (also known as COMIRNATY®, COVID-19 mRNA, Vaccine BNT162b2 or BNT162) or Pfizer COVID-19 Treatment (also known as PAXLOVID™ (nirmatrelvir tablets; ritonavir tablets)), and you are not part of a clinical trial* for this product, click the link below to submit your information:
*If you are involved in a clinical trial for either product, adverse events should be reported to your coordinating study site.
If you cannot use the above website or would like to report an adverse event related to a different Pfizer product, please call Pfizer Safety at(800) 438-1985.
You may also contact the U.S. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns either online at www.fda.gov/medwatchor by calling
(800)-332-1088.
(800)-332-1088.