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PHENELZINE Sulfate Tablets (GREENSTONE LLC)

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PHENELZINE Sulfate Tablets (GREENSTONE LLC) Quick Finder

Suicidality and Antidepressant Drugs

Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other...

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INDICATIONS AND USAGE

Phenelzine sulfate has been found to be effective in depressed patients clinically characterized as "atypical," "nonendogenous," or "neurotic." These patients often have mixed anxiety and depression and...

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DOSAGE AND ADMINISTRATION

Initial dose

The usual starting dose of phenelzine sulfate is one tablet (15 mg) three times a day.

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CONTRAINDICATIONS

Phenelzine sulfate should not be used in patients who are hypersensitive to the drug or its ingredients, with pheochromocytoma, congestive heart failure, severe renal impairment or renal disease, a history...

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WARNINGS

Clinical Worsening and Suicide Risk

Patients with major depressive disorder (MDD), both adult and pediatric, may experience worsening of their depression and...

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ADVERSE REACTIONS

Phenelzine sulfate is a potent inhibitor of monoamine oxidase. Because this enzyme is widely distributed throughout the body, diverse pharmacologic effects can be expected to occur. When they occur, such...

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OVERDOSAGE

Note—For management of hypertensive crises see

Treatment

Intensive symptomatic and supportive treatment may be required....

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DESCRIPTION

Phenelzine sulfate is a potent inhibitor of monoamine oxidase (MAO). Phenelzine sulfate is a hydrazine derivative. It has a molecular weight of 234.27 and is chemically described as C8 H...

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CLINICAL PHARMACOLOGY

Monoamine oxidase is a complex enzyme system, widely distributed throughout the body. Drugs that inhibit monoamine oxidase in the laboratory are associated with a number of clinical effects. Thus, it is...

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HOW SUPPLIED

Each phenelzine sulfate tablet is orange, biconvex, film-coated, and engraved with "P-D 270" and contains phenelzine sulfate equivalent to 15 mg of phenelzine base.

NDC 59762-0119-1. Bottle of 60

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Medication Guide
Antidepressant Medicines, Depression and other Serious Mental Illnesses, and Suicidal Thoughts or Actions

Read the Medication Guide that comes with you or your family member's antidepressant medicine....

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Rx only

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LAB-0456-1.0

February 2011

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