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PFIZERPEN® (penicillin G potassium)

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Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.

PFIZERPEN® Quick Finder

INDICATIONS AND USAGE

Therapy

Penicillin G Potassium for Injection, USP is indicated in the treatment of serious infections caused by susceptible strains of the...

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DOSAGE AND ADMINISTRATION

Buffered Penicillin G Potassium for Injection, USP may be given intravenously or intramuscularly. The usual dose recommendations are as follows:

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CONTRAINDICATIONS

A history of a hypersensitivity (anaphylactic) reaction to any penicillin is a contraindication.

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WARNINGS

Anaphylaxis

Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients on penicillin therapy. These reactions...

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ADVERSE REACTIONS

Body as a whole

The Jarisch-Herxheimer reaction is a systemic reaction, that may occur after the initiation of penicillin therapy in patients with...

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OVERDOSAGE

Dose related toxicity may arise with the use of massive doses of intravenous penicillins (40 to 100 million units per day), particularly in patients with severe renal impairment (see ...

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DESCRIPTION

Buffered Pfizerpen (penicillin G potassium) for Injection is a sterile, pyrogen-free powder for reconstitution. Buffered Pfizerpen for Injection is an antibacterial agent for intramuscular, continuous intravenous...

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CLINICAL PHARMACOLOGY

Aqueous penicillin G is rapidly absorbed following both intramuscular and subcutaneous injection. Initial blood levels following parenteral administration are high but transient. Penicillins bind to...

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HOW SUPPLIED

Buffered Pfizerpen® (penicillin G potassium) for Injection is available in vials containing respectively 5,000,000 units × 10's (NDC 0049-0520-83) and 20,000,000 units × 1's (NDC 0049-0530-28); buffered with...

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To reduce the development of drug-resistant bacteria and maintain the effectiveness of Penicillin G Potassium and other antibacterial drugs, Penicillin G Potassium for Injection...

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