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UNASYN®(ampicillin sodium, sulbactam sodium PHARMACY BULK PACKAGE)

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UNASYN® Quick Finder

INDICATIONS AND USAGE

UNASYN is indicated for the treatment of infections due to susceptible strains of the designated microorganisms in the conditions listed below.

Skin and Skin Structure...

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DOSAGE AND ADMINISTRATION

The pharmacy bulk package is for preparation of solutions for IV infusion only. UNASYN should be administered by slow intravenous injection over at least 10–15 minutes or can also be delivered in...

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CONTRAINDICATIONS

The use of UNASYN is contraindicated in individuals with a history of serious hypersensitivity reactions (e.g., anaphylaxis or Stevens-Johnson syndrome) to ampicillin, sulbactam or to other beta-lactam...

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WARNINGS

Hypersensitivity

Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients on penicillin therapy. These...

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ADVERSE REACTIONS

Adult Patients

UNASYN is generally well tolerated. The following adverse reactions have been reported in clinical trials.

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OVERDOSAGE

Neurological adverse reactions, including convulsions, may occur with the attainment of high CSF levels of beta-lactams. Ampicillin may be removed from circulation by hemodialysis. The molecular weight, degree of...

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DESCRIPTION

UNASYN is an injectable antibacterial combination consisting of the semisynthetic antibacterial ampicillin sodium and the beta-lactamase inhibitor sulbactam sodium for intravenous and intramuscular administration...

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CLINICAL PHARMACOLOGY

General

Immediately after completion of a 15-minute intravenous infusion of UNASYN, peak serum concentrations of ampicillin and sulbactam are...

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CLINICAL STUDIES

Skin and Skin Structure Infections in Pediatric Patients

Data from a controlled clinical trial conducted in pediatric patients provided evidence...

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HOW SUPPLIED

UNASYN (ampicillin sodium/sulbactam sodium), a sterile off-white dry powder, is available in Pharmacy Bulk Package containing ampicillin sodium and sulbactam sodium equivalent to 10 g ampicillin and 5 g...

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