HIGHLIGHTS OF PRESCRIBING INFORMATIONThese highlights do not include all the... |
Did you find an answer to your question?
Yes
No
If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.
Our medical information is accurate, up to date, and scientifically balanced.
morphine sulfate injection, USP ISECURE, CARPUJECT
If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.
Our medical information is accurate, up to date, and scientifically balanced.
morphine sulfate injection, USP ISECURE, CARPUJECT Quick Finder
Highlights
Boxed Warning
WARNING: ADDICTION, ABUSE, AND MISUSE; LIFE-THREATENING RESPIRATORY DEPRESSION; NEONATAL OPIOID WITHDRAWAL SYNDROME; and RISKS FROM CONCOMITANT USE WITH BENZODIAZEPINES OR OTHER CNS DEPRESSANTS
...
Did you find an answer to your question?
Yes
No
Indications and Usage
1 INDICATIONS AND USAGE
Morphine Sulfate Injection is indicated for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.
...
Did you find an answer to your question?
Yes
No
Dosage and Administration
2 DOSAGE AND ADMINISTRATION
2.1 Important Dosage and Administration Instructions
Morphine Sulfate Injection is for intravenous administration.
Morphine Sulfate...
Did you find an answer to your question?
Yes
No
Dosage Forms and Strengths
...
3 DOSAGE FORMS AND STRENGTHS
Morphine Sulfate Injection, USP is available in the following strengths for intravenous (IV) administration.
Did you find an answer to your question?
Yes
No
Contraindications
4 CONTRAINDICATIONS
Morphine Sulfate Injection is contraindicated in patients with:
- Significant respiratory depression [see Warnings and Precautions (5.2)]...
Did you find an answer to your question?
Yes
No
Warnings and Precautions
5 WARNINGS AND PRECAUTIONS
5.1 Addiction, Abuse, and Misuse
Morphine Sulfate Injection contains morphine, a Schedule II controlled substance. As an opioid, Morphine...
Did you find an answer to your question?
Yes
No
Drug Interactions
7 DRUG INTERACTIONS
Table 1 includes clinically significant drug interactions with Morphine Sulfate Injection.
Did you find an answer to your question?
Yes
No
Use in Specific Populations
8 USE IN SPECIFIC POPULATIONS
8.1 Pregnancy
Risk Summary
Prolonged use of opioid...
Did you find an answer to your question?
Yes
No
Drug Abuse and Dependence
...
9 DRUG ABUSE AND DEPENDENCE
9.1 Controlled Substance
Morphine Sulfate Injection contains morphine, a Schedule II controlled substance.
Did you find an answer to your question?
Yes
No
Overdosage
10 OVERDOSAGE
Clinical Presentation
Acute overdose with Morphine Sulfate Injection can be manifested by respiratory depression, somnolence...
Did you find an answer to your question?
Yes
No
Description
11 DESCRIPTION
Morphine Sulfate Injection, USP is an opioid agonist, available as 2 mg/mL, 4 mg/mL, 8 mg/mL, 10 mg/mL, and 15 mg/mL (1 mL fill in 1.5 mL iSecure™ Single-dose Prefilled Syringe with Luer Lock) and 2 mg/mL, 4...
Did you find an answer to your question?
Yes
No
Clinical Pharmacology
12 CLINICAL PHARMACOLOGY
12.1 Mechanism of Action
Morphine is a full opioid agonist and is relatively selective for the mu-opioid receptor, although it can bind to...
Did you find an answer to your question?
Yes
No
Nonclinical Toxicology
13 NONCLINICAL TOXICOLOGY
13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility
Carcinogenesis...
Did you find an answer to your question?
Yes
No
How Supplied/Storage and Handling
16 HOW SUPPLIED/STORAGE AND HANDLING
Morphine Sulfate Injection, USP is supplied as a sterile solution in single-dose Carpuject™ cartridges and iSecure™ syringes for intravenous administration as follows:
...
Did you find an answer to your question?
Yes
No
Medication Guide
17 PATIENT COUNSELING INFORMATION
Serotonin Syndrome
Opioids can cause a rare but potentially life-threatening condition resulting from...
Did you find an answer to your question?
Yes
No
Instructions For Use
INSTRUCTIONS FOR USE
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Do not use if color is darker than pale...
Did you find an answer to your question?
Yes
No
Did you find an answer to your question?
Yes
No
Didn’t find what you were looking for? Contact us.
To interact with the Medical Information Digital Assistant click here.
Contact Pfizer Medical Information to speak with a professional regarding your medical question on a Pfizer prescription product: (800) 438-1985
Report Adverse Event
To report an adverse event related to Pfizer-BioNTech COVID-19 Vaccine (also known as COMIRNATY®, COVID-19 mRNA, Vaccine BNT162b2 or BNT162) or Pfizer COVID-19 Treatment (also known as PAXLOVID™ (nirmatrelvir tablets; ritonavir tablets)), and you are not part of a clinical trial* for this product, click the link below to submit your information:
*If you are involved in a clinical trial for either product, adverse events should be reported to your coordinating study site.
If you cannot use the above website or would like to report an adverse event related to a different Pfizer product, please call Pfizer Safety at(800) 438-1985.
You may also contact the U.S. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns either online at www.fda.gov/medwatchor by calling
(800)-332-1088.
(800)-332-1088.