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LINCOCIN® (lincomycin HCl)

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LINCOCIN® Quick Finder

WARNING

Clostridioides difficile associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including LINCOCIN and may range in severity from mild diarrhea to fatal colitis. Treatment with...

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INDICATIONS AND USAGE

LINCOCIN is indicated in the treatment of serious infections due to susceptible strains of streptococci, pneumococci, and staphylococci. Its use should be reserved for penicillin-allergic patients or...

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DOSAGE AND ADMINISTRATION

If significant diarrhea occurs during therapy, LINCOCIN should be discontinued. (see BOXED WARNING)

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CONTRAINDICATIONS

LINCOCIN is contraindicated in patients previously found to be hypersensitive to lincomycin or clindamycin.

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ADVERSE REACTIONS

The following adverse reactions have been reported with the use of lincomycin.

Gastrointestinal disorders

Diarrhea, nausea,...

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OVERDOSAGE

Serum concentrations of lincomycin are not appreciably affected by hemodialysis and peritoneal dialysis.

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DESCRIPTION

LINCOCIN (lincomycin injection, USP) is a sterile solution containing lincomycin hydrochloride which is the monohydrated salt of lincomycin, a lincosamide antibacterial produced by the growth of a member of the...

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CLINICAL PHARMACOLOGY

Intramuscular administration of a single dose of 600 mg of lincomycin produces average peak serum concentrations of 11.6 mcg/mL at 60 minutes and maintains therapeutic concentrations for 17 to 20 hours...

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ANIMAL PHARMACOLOGY

In vivo experimental animal studies demonstrated the effectiveness of LINCOCIN preparations (lincomycin) in protecting animals infected with Streptococcus...

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HOW SUPPLIED

LINCOCIN (lincomycin injection, USP) is available as a sterile, clear, and colorless solution in the following strength and package sizes:

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Sterile Solution for Intramuscular and Intravenous Use

To reduce the development of drug-resistant bacteria and maintain the effectiveness of LINCOCIN and other...

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