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lidocaine hydrochloride 5% and 7.5% Dextrose (FOR SPINAL ANESTHESIA)

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lidocaine hydrochloride 5% and 7.5% Dextrose (FOR SPINAL ANESTHESIA) Quick Finder

INDICATIONS AND USAGE

5% Lidocaine Hydrochloride and 7.5% Dextrose Injection, USP is indicated for the production of spinal anesthesia when the accepted procedures for this technique as described in standard textbooks are...

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DOSAGE AND ADMINISTRATION

Spinal anesthesia with 5% Lidocaine Hydrochloride and 7.5% Dextrose Injection, USP may be induced in the right or left lateral recumbent or the sitting position. Since this is a hyperbaric solution...

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CONTRAINDICATIONS

Lidocaine is contraindicated in patients with a known history of hypersensitivity to local anesthetics of the amide type.

The following conditions preclude the use of spinal anesthesia:

...
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WARNINGS

5% LIDOCAINE HYDROCHLORIDE AND 7.5% DEXTROSE INJECTION, USP FOR SPINAL ANESTHESIA SHOULD BE EMPLOYED ONLY BY CLINICIANS WHO ARE WELL VERSED IN DIAGNOSIS AND MANAGEMENT OF DOSE-RELATED TOXICITY AND OTHER ACUTE...

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ADVERSE REACTIONS

Adverse experiences following the administration of lidocaine are similar in nature to those observed with other amide local anesthetic agents. These adverse experiences are, in general, dose-related and...

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OVERDOSAGE

Acute emergencies from local anesthetics are generally related to high plasma levels encountered during therapeutic use of local anesthetics or to unintended subarachnoid injection of local anesthetic solution (see...

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DESCRIPTION

5% Lidocaine Hydrochloride and 7.5% Dextrose Injection, USP is a sterile, nonpyrogenic, hyperbaric solution for use in spinal anesthesia.

5% Lidocaine Hydrochloride and 7.5% Dextrose Injection, USP contains...

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CLINICAL PHARMACOLOGY

Mechanism of action

Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of...

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  1. Lambert DH and Hurley RJ: Cauda Equina syndrome and continuous spinal anesthesia. Anesth and Analg 72:817–9, 1991.
  2. Ready, LB, et al: Neurotoxicity of local anesthetics in rabbits. Anesthesiology 63:364–70, 1985.
  3. ...
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HOW SUPPLIED

5% Lidocaine Hydrochloride and 7.5% Dextrose Injection, USP, is supplied in the following:

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Ampul

Single-dose Container

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