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heparin sodium injection CARPUJECT

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heparin sodium injection CARPUJECT Quick Finder

HIGHLIGHTS OF PRESCRIBING INFORMATION

These highlights do not include all the...
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1 INDICATIONS AND USAGE

Heparin Sodium Injection is indicated for:

  • Prophylaxis and treatment of venous thrombosis and, pulmonary embolism;
  • Prevention of postoperative deep venous thrombosis...
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2 DOSAGE AND ADMINISTRATION

2.1 Preparation for Administration

Confirm the choice of the correct Heparin Sodium Injection vial or cartridge prior to administration of...

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3 DOSAGE FORMS AND STRENGTHS

  • Heparin Sodium: 5,000 USP Units/0.5 mL, Preservative free
  • Heparin Sodium: 5,000 USP Units/1 mL
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4 CONTRAINDICATIONS

The use of Heparin Sodium Injection is contraindicated in patients with the following conditions:

  • History of heparin-induced thrombocytopenia and heparin-induced thrombocytopenia...
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5 WARNINGS AND PRECAUTIONS

5.1 Fatal Medication Errors

Do not use Heparin Sodium Injection as a "catheter lock flush" product. Heparin Sodium Injection is supplied in...

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6 ADVERSE REACTIONS

The following clinically significant adverse reactions are described elsewhere in the labeling:

  • Hemorrhage [see

    6.2 Postmarketing Experience

    ...
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7 DRUG INTERACTIONS

7.1 Oral Anticoagulants

Heparin Sodium may prolong the one-stage prothrombin time. Therefore, when Heparin Sodium is given with dicumarol or...

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8 USE IN SPECIFIC POPULATIONS

8.1 Pregnancy

Risk Summary

There are no available...

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10 OVERDOSAGE

Bleeding is the chief sign of heparin overdosage.

Neutralization of Heparin Effect

When clinical...

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11 DESCRIPTION

Heparin is a heterogenous group of straight-chain anionic mucopolysaccharides, called glycosaminoglycans, having anticoagulant properties. Although others may be present, the main sugars occurring in heparin...

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12 CLINICAL PHARMACOLOGY

12.1 Mechanism of Action

Heparin interacts with the naturally occurring plasma protein, Antithrombin III, to induce a conformational change,...

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13 NONCLINICAL TOXICOLOGY

13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility

No long-term studies in animals have been performed to evaluate carcinogenic...

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16 HOW SUPPLIED/STORAGE AND HANDLING

Heparin Sodium is supplied in the following strengths and package configurations:

...
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17 PATIENT COUNSELING INFORMATION

Hemorrhage

Inform patients that it may take them longer than usual to stop bleeding, that they may...

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Carpuject™ Single-dose cartridges with Luer Lock are packaged in a Slim-Pak™ tamper detection package. Note that a needle is not included.

...
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