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cytarabine injection - 500 MG/25 ML MULTI-DOSE VIA

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cytarabine injection - 500 MG/25 ML MULTI-DOSE VIA Quick Finder

WARNING

Only physicians experienced in cancer chemotherapy should use Cytarabine Injection.

For induction therapy patients should be treated in a facility with laboratory and supportive resources sufficient to monitor drug tolerance and protect...

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INDICATIONS AND USAGE

Cytarabine in combination with other approved anticancer drugs is indicated for remission induction in acute non-lymphocytic leukemia of adults and children. It has also been found useful in the...

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DOSAGE AND ADMINISTRATION

Cytarabine is not active orally. The schedule and method of administration varies with the program of therapy to be used. Cytarabine Injection may be given by intravenous infusion or injection or...

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CONTRAINDICATIONS

Cytarabine is contraindicated in those patients who are hypersensitive to the drug.

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ADVERSE REACTIONS

Expected Reactions: Because cytarabine is a bone marrow suppressant, anemia, leukopenia, thrombocytopenia, megaloblastosis and...

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OVERDOSAGE

There is no antidote for cytarabine overdosage. Doses of 4.5 g/m2 by intravenous infusion over 1 hour every 12 hours for 12 doses has caused an unacceptable increase in irreversible CNS...

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DESCRIPTION

Cytarabine Injection, an antineoplastic agent, is a sterile preserved solution for intravenous or subcutaneous administration and is available in 20 mg/mL (500 mg/25 mL) multiple-dose vial. Each mL contains: 20 ...

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CLINICAL PHARMACOLOGY

Cell Culture Studies: Cytarabine is cytotoxic to a wide variety of proliferating mammalian cells in culture. It exhibits cell...

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REFERENCES

1.
Recommendations for the Safe Handling of Parenteral Antineoplastic Drugs, NIH Publications No. 83-2621. For sale by the Superintendent of Documents, U.S. Government Printing Office, Washington, D.C. 20402....
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HOW SUPPLIED

Cytarabine Injection is available as follows:

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NOT FOR INTRATHECAL USE - CONTAINS BENZYL ALCOHOL
FOR INTRAVENOUS OR SUBCUTANEOUS USE ONLY

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