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cytarabine injection - PHARMACY BULK PACKAGE

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cytarabine injection - PHARMACY BULK PACKAGE Quick Finder

WARNING

Only physicians experienced in cancer chemotherapy should use Cytarabine Injection.

For induction therapy patients should be treated in a facility with laboratory and supportive resources sufficient to monitor drug tolerance and protect...

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INDICATIONS AND USAGE

Cytarabine in combination with other approved anticancer drugs is indicated for remission induction in acute non-lymphocytic leukemia of adults and children. It has also been found useful in the...

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DOSAGE AND ADMINISTRATION

Cytarabine Injection (non-preserved) can be administered by intravenous injection or infusion, subcutaneously, or intrathecally. However, the intent of this...

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CONTRAINDICATIONS

Cytarabine Injection is contraindicated in those patients who are hypersensitive to the drug.

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WARNINGS

(See boxed WARNING)

Cytarabine is a potent bone marrow suppressant. Therapy should be started...

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ADVERSE REACTIONS

Expected Reactions: Because cytarabine is a bone marrow suppressant, anemia, leukopenia, thrombocytopenia, megaloblastosis and reduced reticulocytes...

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OVERDOSAGE

There is no antidote for cytarabine overdosage. Doses of 4.5 g/m2 by intravenous infusion over 1 hour every 12 hours for 12 doses has caused an unacceptable increase in irreversible CNS...

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DESCRIPTION

Cytarabine Injection, an antineoplastic, is a sterile isotonic solution for intravenous and subcutaneous use, which contains no preservative and is available in 20 mg/mL (1000 mg/50 mL) Pharmacy Bulk Package....

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CLINICAL PHARMACOLOGY

Cell Culture Studies: Cytarabine is cytotoxic to a wide variety of proliferating mammalian cells in culture. It exhibits cell phase specificity,...

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REFERENCES

1.
Recommendations for the Safe handling of Parenteral Antineoplastic Drugs, NIH Publications No. 83-2621. For sale by the Superintendent of Documents, U.S. Government Printing Office, Washington, D.C. 20402.
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HOW SUPPLIED

Cytarabine Injection is available as follows:

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  PHARMACY BULK PACKAGE - NOT FOR DIRECT INFUSION 

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