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CLEOCIN® Pediatric (clindamycin)

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CLEOCIN® Pediatric Quick Finder

WARNING

Clostridioides difficile-associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including clindamycin and may range in severity from mild diarrhea to fatal colitis. Treatment with...

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INDICATIONS AND USAGE

CLEOCIN PEDIATRIC (clindamycin palmitate HCl) is indicated in the treatment of serious infections caused by susceptible anaerobic bacteria.

Clindamycin is also indicated in the treatment of...

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DOSAGE AND ADMINISTRATION

If significant diarrhea occurs during therapy, this antibiotic should be discontinued (see BOXED WARNING).

Concomitant administration of...

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CONTRAINDICATIONS

This drug is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin.

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ADVERSE REACTIONS

The following reactions have been reported with the use of clindamycin.

Infections and infestations: Clostridioides difficile colitis

...

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OVERDOSAGE

Significant mortality was observed in mice at an intravenous dose of 855 mg/kg and in rats at an oral or subcutaneous dose of approximately 2618 mg/kg. In the mice, convulsions and depression were observed....

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DESCRIPTION

Clindamycin palmitate hydrochloride is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid. Clindamycin is a semisynthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R...

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CLINICAL PHARMACOLOGY

Human Pharmacology

Absorption

Blood level studies comparing...

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References

1.
Smith RB, Phillips JP: Evaluation of CLEOCIN HCl and CLEOCIN Phosphate in an Aged Population. Upjohn TR 8147-82-9122-021, December 1982.
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HOW SUPPLIED

CLEOCIN PEDIATRIC Flavored Granules for oral solution is available in bottles of 100 mL (NDC 0009-0760-04).

When reconstituted as directed, each bottle yields a solution containing 75 mg of clindamycin per...

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To reduce the development of drug-resistant bacteria and maintain the effectiveness of CLEOCIN PEDIATRIC and other antibacterial drugs, CLEOCIN PEDIATRIC should be used only to...

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