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BICILLIN® L-A (penicillin G benzathine)

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BICILLIN® L-A Quick Finder

WARNING

NOT FOR INTRAVENOUS USE. DO NOT INJECT INTRAVENOUSLY OR ADMIX WITH OTHER INTRAVENOUS SOLUTIONS. THERE HAVE BEEN REPORTS OF INADVERTENT INTRAVENOUS ADMINISTRATION OF PENICILLIN G BENZATHINE WHICH...

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INDICATIONS AND USAGE

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Bicillin L-A and other antibacterial drugs, Bicillin L-A should be used only to treat or prevent infections that...

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DOSAGE AND ADMINISTRATION

Streptococcal (Group A) Upper Respiratory Infections (for example, pharyngitis)

Adults—a single injection of 1,200,000 units; older pediatric patients—a single...

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CONTRAINDICATIONS

A history of a previous hypersensitivity reaction to any of the penicillins is a contraindication.

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WARNINGS

WARNING

NOT FOR INTRAVENOUS USE. DO NOT INJECT INTRAVENOUSLY OR ADMIX WITH OTHER INTRAVENOUS SOLUTIONS. THERE HAVE BEEN REPORTS OF...

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ADVERSE REACTIONS

As with other penicillins, untoward reactions of the sensitivity phenomena are likely to occur, particularly in individuals who have previously demonstrated hypersensitivity to penicillins or in those with...

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OVERDOSAGE

Penicillin in overdosage has the potential to cause neuromuscular hyperirritability or convulsive seizures.

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Description

Bicillin L-A (penicillin G benzathine injectable suspension) is available for deep intramuscular injection. Penicillin G benzathine is prepared by the reaction of dibenzylethylene diamine with two molecules of...

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CLINICAL PHARMACOLOGY

General

Penicillin G benzathine has an extremely low solubility and, thus, the drug is slowly released from intramuscular injection sites. The...

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REFERENCES

1.
SHAW, E.: Transverse myelitis from injection of penicillin. Am. J. Dis. Child., 111:548, 1966.
2.
KNOWLES, J.: Accidental intra-arterial injection of penicillin....
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HOW SUPPLIED

Bicillin L-A (penicillin G benzathine injectable suspension) is supplied in packages of 10 disposable syringes as follows:

1 mL size, containing 600,000 units per syringe, (21 gauge, thin-wall 1-inch...

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For deep IM injection only.

To reduce the development of drug-resistant...

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