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bacitracin, USP

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bacitracin, USP Quick Finder

WARNING

Nephrotoxicity: Bacitracin in parenteral (intramuscular) therapy may cause renal failure due to tubular and glomerular necrosis. Its use should be restricted to infants with staphylococcal pneumonia and empyema when due to organisms shown to be...

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INDICATIONS AND USAGE

In accordance with the statements in the "Warning Box", the use of intramuscular bacitracin is limited to the treatment of infants with pneumonia and empyema caused by staphylococci shown to be...

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DOSAGE AND ADMINISTRATION

TO BE ADMINISTERED INTRAMUSCULARLY ONLY

Infant dose: For infants under 2500 grams—900 units/kg/24 hours in 2 or 3 divided doses. For infants over 2500 grams—1,000 units/kg/24 hours, in 2 or 3...

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CONTRAINDICATIONS

This drug is contraindicated in those individuals with a history of previous hypersensitivity or toxic reaction to it.

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WARNINGS and PRECAUTIONS

See "Warning Box" for precautions in regard to kidney toxicity associated with intramuscular use of bacitracin.

Clostridium difficile associated diarrhea (CDAD) has...

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ADVERSE REACTIONS

Nephrotoxic reactions—Albuminuria, cylindruria, azotemia. Rising blood levels without any increase in dosage.

Other reactions—Nausea and vomiting....

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DESCRIPTION

Sterile Bacitracin, USP is an antibiotic for intramuscular administration. Bacitracin is derived from cultures of Bacillus subtilis (Tracey). It is a white to pale buff, hygroscopic powder, odorless or having a...

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CLINICAL PHARMACOLOGY

Bacitracin exerts pronounced antibacterial action in vitro against a variety of gram-positive and a few gram-negative organisms. However, among systemic diseases, only...

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HOW SUPPLIED

Sterile Bacitracin, USP is available in a vial (1's) containing 50,000 units (NDC 0009-0233-01) and as a pack of ten vials (10's) each containing 50,000 units (NDC 0009-0233-03).

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To reduce the development of drug-resistant bacteria and maintain the effectiveness of Bacitracin and other antibacterial drugs, Bacitracin should be used only to treat...

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