pancuronium bromide injection, USP How Supplied/Storage and Handling | Pfizer Medical Information - US

HOW SUPPLIED

Pancuronium Bromide Injection, USP is supplied as follows:

Unit of Sale	Concentration
NDC 0409-4646-01 Tray of 25 Multiple-dose Fliptop Vials	10 mg/10 mL (1 mg/mL)

STORAGE

Store in refrigerator 2° to 8°C (36° to 46°F).

The 10 mL vial will maintain full clinical potency for up to six months at room temperature.

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Resources

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INDICATIONS AND USAGE

Pancuronium bromide is indicated as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

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DOSAGE AND ADMINISTRATION

Pancuronium Bromide Injection, USP is for intravenous use only. This drug should be administered by or under the supervision of experienced clinicians familiar with the use of neuromuscular blocking...

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CONTRAINDICATIONS

Pancuronium Bromide Injection, USP is contraindicated in patients known to be hypersensitive to the drug.

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WARNINGS

PANCURONIUM BROMIDE INJECTION, USP SHOULD BE ADMINISTERED IN CAREFULLY ADJUSTED DOSES BY OR UNDER THE SUPERVISION OF EXPERIENCED CLINICIANS WHO ARE FAMILIAR WITH ITS ACTIONS AND THE POSSIBLE COMPLICATIONS THAT MIGHT...

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ADVERSE REACTIONS

Neuromuscular

The most frequent adverse reaction to nondepolarizing blocking agents as a class consists of an extension of the drug's pharmacological...

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OVERDOSAGE

The possibility of iatrogenic overdosage can be minimized by carefully monitoring the muscle twitch response to peripheral nerve stimulation.

Excessive doses of pancuronium bromide can be expected to produce...

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DESCRIPTION

Pancuronium Bromide is a nondepolarizing neuromuscular blocking agent chemically designated as the aminosteroid 2β, 16β - dipiperidino-5α-androstane-3α, 17-β diol diacetate dimethobromide, C35...

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CLINICAL PHARMACOLOGY

Pancuronium bromide is a nondepolarizing neuromuscular blocking agent possessing all of the characteristic pharmacological actions of this class of drugs (curariform). It acts by competing for...

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HOW SUPPLIED

Pancuronium Bromide Injection, USP is supplied as follows:

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Report Adverse Event

Pfizer Safety

To report an adverse event related to a Pfizer product and you are not part of a clinical trial* for this product, click the link below to submit your information: Pfizer Safety Reporting Site

*If you are involved in a clinical trial for either product, adverse events should be reported to your coordinating study site.

If you cannot use the above website to report an adverse event related to a Pfizer product, please call Pfizer Medical Information at (800) 438-1985.

FDA Medwatch

You may also contact the U.S. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns either online at www.fda.gov/medwatchor by calling
(800)-332-1088.