pancuronium bromide injection, USP Description | Pfizer Medical Information

DESCRIPTION

Pancuronium Bromide is a nondepolarizing neuromuscular blocking agent chemically designated as the aminosteroid 2β, 16β - dipiperidino-5α-androstane-3α, 17-β diol diacetate dimethobromide, C35H60Br2N2O4. It is a fine white odorless powder which is soluble in water, alcohol and chloroform.

It has the following structural formula:

Pancuronium Bromide Injection, USP is available in sterile, isotonic, nonpyrogenic solution for injection. Each mL contains pancuronium bromide 1 mg; sodium acetate, anhydrous 1.2 mg; benzyl alcohol 10 mg as preservative. Sodium chloride added to adjust tonicity. May contain acetic acid and/or sodium hydroxide for pH adjustment. pH is 4.0 (3.8 to 4.2).

pancuronium bromide injection, USP Quick Finder

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INDICATIONS AND USAGE

Pancuronium bromide is indicated as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.