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M.V.I. ADULT Description (multi-vitamin infusion - ADULT)

11 DESCRIPTION

M.V.I. Adult (multiple vitamins injection) is a sterile product consisting of two vials provided as a single dose or as a pharmacy bulk package for intravenous use intended for administration by intravenous infusion after dilution.

Table 1 provides the strengths of the vitamins provided in vial 1 and vial 2:

Table 1: M.V.I. ADULT FORMULATION (INTENDED FOR AGES 11 AND OLDER)

Vial 1*

Fat Soluble Vitamins**

Ingredient

Amount per Unit Dose

Vitamin A (retinol)

1 mga

Vitamin D (ergocalciferol)

5 mcgb

Vitamin E (dl-alpha-tocopheryl acetate)

10 mgc

Vitamin K (phytonadione)

150 mcg

Water Soluble Vitamins

Vitamin C (ascorbic acid)

200 mg

Niacinamide

40 mg

Vitamin B2 (as riboflavin 5-phosphate sodium)

3.6 mg

Vitamin B1 (thiamine)

6 mg

Vitamin B6 (pyridoxine HCl)

6 mg

Dexpanthenol (d-pantothenyl alcohol)

15 mg

*    With 30% propylene glycol and 2% gentisic acid ethanolamide as stabilizers and preservatives; sodium hydroxide for pH adjustment; 1.6% polysorbate 80; 0.028% polysorbate 20; 0.002% butylated hydroxytoluene; 0.0005% butylated hydroxyanisole.
**   Fat soluble vitamins A, D, E and K are water solubilized with polysorbate 80.
(a) 1 mg vitamin A equals 3,300 USP units.
(b) 5 mcg ergocalciferol equals 200 USP units.
(c) 10 mg vitamin E equals 10 USP units.

Vial 2*

Biotin

60 mcg

Folic acid

600 mcg

B12 (cyanocobalamin)

5 mcg

*      With 30% propylene glycol; and citric acid, sodium citrate, and sodium hydroxide for pH adjustment.

Multiple vitamin preparation for intravenous infusion:

M.V.I. Adult (multiple vitamins injection) makes available a combination of fat-soluble and water-soluble vitamins in an aqueous solution, formulated for incorporation into intravenous infusions. The liposoluble vitamins A, D, E, and K have been solubilized in an aqueous medium with polysorbate 80, permitting intravenous administration of these vitamins.

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