
If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.
midazolam injection, USP PRESERVATIVE FREE
If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.
midazolam injection, USP PRESERVATIVE FREE Quick Finder
INDICATIONS AND USAGE
Midazolam injection is indicated:
- •
- intramuscularly or intravenously for preoperative sedation/anxiolysis/amnesia;
- •
- intravenously as an agent for sedation/anxiolysis/...
DOSAGE AND ADMINISTRATION
Midazolam injection is a potent sedative agent that requires slow administration and individualization of dosage. Clinical experience has shown midazolam to be 3 to 4 times as...
CONTRAINDICATIONS
Injectable midazolam is contraindicated in patients with a known hypersensitivity to the drug. Benzodiazepines are contraindicated in patients with acute narrow-angle glaucoma. Benzodiazepines may be used...
WARNINGS
Personnel and Equipment for Monitoring and Resuscitation
Prior to the intravenous administration of midazolam in any dose, the immediate availability of...
DRUG ABUSE AND DEPENDENCE
Midazolam Injection contains midazolam a Schedule IV control substance.
Midazolam was actively self-administered in primate models used to assess the positive reinforcing effects of...
OVERDOSAGE
Clinical Presentation
Overdosage of benzodiazepines is characterized by central nervous system depression ranging from drowsiness to coma. In mild to...
DESCRIPTION
Midazolam hydrochloride injection is a water-soluble benzodiazepine available as a sterile, nonpyrogenic parenteral dosage form for intravenous or intramuscular injection. Each mL contains midazolam hydrochloride...
CLINICAL PHARMACOLOGY
Midazolam is a short-acting benzodiazepine central nervous system (CNS) depressant.
Pharmacodynamics
The effects of...
ANIMAL TOXICOLOGY AND/OR PHARMACOLOGY
Published studies in animals demonstrate that the use of anesthetic agents during the period of rapid brain growth or synaptogenesis results in widespread neuronal and oligodendrocyte...
HOW SUPPLIED
Package configurations containing preservative-free midazolam hydrochloride equivalent to 1 mg midazolam/mL:
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