METOPROLOL (metoprolol tartrate injection, USP - CARPUJECT)

metoprolol tartrate injection, USP - CARPUJECT Quick Finder

Pfizer samples (for eligible HCPs)

Requests for samples of prescription medications can be made by contacting Pfizer for Professionals at 1-800-505-4426 or by visiting the PfizerPro website www.pfizerpro.com.
Report an adverse event or concern about the quality of a Pfizer product

To report an adverse event related to Pfizer-BioNTech COVID-19 Vaccine (also known as COMIRNATY®, COVID-19 mRNA, Vaccine BNT162b2 or BNT162) or Pfizer COVID-19 Treatment (also known as PAXLOVID™ (nirmatrelvir tablets; ritonavir tablets)), and you are not part of a clinical trial* for this product, click the link below to submit your information:
Pfizer Safety Reporting Site
*If you are involved in a clinical trial for either product, adverse events should be reported to your coordinating study site.
If you cannot use the above website or would like to report an adverse event related to a different Pfizer product, please call Pfizer Safety at (800) 438-1985.
If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly by visiting www.fda.gov/medwatch or by calling (800)-332-1088.
Assistance programs (for eligible patients)

Pfizer RxPathways connects eligible patients to a range of assistance programs that offer insurance support, co-pay help, and medicines for free or at a savings. Patients and physicians can contact RxPathways at (866) 706-2400 or visit the website for more information on these programs www.pfizerrxpathways.com.
Resources

Download Prescribing Information

Show All Hide All

HIGHLIGHTS OF PRESCRIBING INFORMATION

These highlights do not include all the...

Did you find an answer to your question? Yes No

1 INDICATIONS AND USAGE

Metoprolol tartrate injection is indicated in the treatment of definite or suspected acute myocardial infarction in hemodynamically stable patients to reduce cardiovascular mortality when used in...

Did you find an answer to your question? Yes No

2 DOSAGE AND ADMINISTRATION

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.

Initiate treatment in a...

Did you find an answer to your question? Yes No

3 DOSAGE FORMS AND STRENGTHS

Injection: 5 mg metoprolol tartrate supplied in 5 mL Carpuject Luer Lock Glass Syringes (no needle) (3)

Did you find an answer to your question? Yes No

4 CONTRAINDICATIONS

Hypersensitivity to metoprolol tartrate and related derivatives, or to any of the excipients; hypersensitivity to other beta-blockers (cross sensitivity between beta-blockers can occur).

Metoprolol...

Did you find an answer to your question? Yes No

5 WARNINGS AND PRECAUTIONS

5.1 Bradycardia

Bradycardia, including sinus pause, heart block, and cardiac arrest have occurred with the use of Metoprolol tartrate....

Did you find an answer to your question? Yes No

6 ADVERSE REACTIONS

The following adverse reactions are described elsewhere in labeling:

Worsening angina or myocardial infarction [see Warnings and Precautions (5...

Did you find an answer to your question? Yes No

7 DRUG INTERACTIONS

7.1 Catecholamine Depleting Drugs and Monoamine Oxidate (MAO) Inhibitors

Catecholamine depleting drugs (e.g., reserpine) and monoamine oxidase (...

Did you find an answer to your question? Yes No

8 USE IN SPECIFIC POPULATIONS

8.1 Pregnancy

Risk Summary

Available data from...

Did you find an answer to your question? Yes No

10 OVERDOSAGE

Signs and Symptoms - Overdosage of metoprolol may lead to severe bradycardia,...

Did you find an answer to your question? Yes No

11 DESCRIPTION

Metoprolol tartrate injection, USP is a selective beta1-adrenoreceptor blocking agent, available in 5 mL ampuls and 5 mL Carpuject™ sterile cartridge units, for intravenous...

Did you find an answer to your question? Yes No

12 CLINICAL PHARMACOLOGY

12.1 Mechanism of Action

Metoprolol is a beta1-selective (cardioselective) adrenergic receptor blocking agent. This...

Did you find an answer to your question? Yes No

13 NONCLINICAL TOXICOLOGY

13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility

Long-term studies in animals have been conducted to evaluate the carcinogenic...

Did you find an answer to your question? Yes No

14 CLINICAL STUDIES

In a large (1,395 patients randomized), double-blind, placebo-controlled clinical study, metoprolol tartrate was shown to reduce 3-month mortality by 36% in patients with suspected or definite myocardial...

Did you find an answer to your question? Yes No

16 HOW SUPPLIED/STORAGE AND HANDLING

Metoprolol tartrate injection, USP is available as:

...

Did you find an answer to your question? Yes No

17 PATIENT COUNSELING INFORMATION

Advise patients (1) to avoid operating automobiles and machinery or engaging in other tasks requiring alertness until the patient's response to therapy with metoprolol tartrate has been...

Did you find an answer to your question? Yes No

Logo

Distributed by
Hospira, Inc., Lake Forest, IL 60045 USA

LAB-1112-4.0

Did you find an answer to your question? Yes No

Didn’t find what you were looking for? Contact us.

MI Digital Assistant

Chat online with Pfizer Medical Information regarding your inquiry on a Pfizer medicine.

Call 800-438-1985^*

*Contact Medical Information. 8AM-9PM ET Monday to Friday; excluding holidays.

Medical Inquiry

Submit a medical question for Pfizer prescription products.

Report Adverse Event

Pfizer Safety

To report an adverse event related to Pfizer-BioNTech COVID-19 Vaccine (also known as COMIRNATY®, COVID-19 mRNA, Vaccine BNT162b2 or BNT162) or Pfizer COVID-19 Treatment (also known as PAXLOVID™ (nirmatrelvir tablets; ritonavir tablets)), and you are not part of a clinical trial* for this product, click the link below to submit your information:

Pfizer Safety Reporting Site

*If you are involved in a clinical trial for either product, adverse events should be reported to your coordinating study site.

If you cannot use the above website or would like to report an adverse event related to a different Pfizer product, please call Pfizer Safety at
(800) 438-1985.

FDA Medwatch

You may also contact the U.S. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns either online at www.fda.gov/medwatchor by calling
(800)-332-1088.