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Methotrexate Vial How Supplied/Storage and Handling


How Supplied

Methotrexate Injection is a clear, yellow, sterile solution available with preservative (multiple-dose vials) and preservative-free (single-dose vials) as follows:

Strength/Fill volumeNDC numberPack style
With Preservative
50 mg/2 mL (25 mg/mL)61703-350-38Carton containing five (5) multiple-dose vials
1 g/40 mL (25 mg/mL)61703-408-41Carton containing one (1) single-dose vial
Carton contentsNDC
Methotrexate Injection, With Preservative, 5 multiple-dose vials
50 mg/2 mL (25 mg/mL)61703-350-38
Preservative-free Methotrexate Injection, 1 single-dose vial
1 g/40 mL (25 mg/mL)61703-408-41

Storage and Handling

Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F) [see USP Controlled Room Temperature]. Protect from light.

After first puncture, store multiple-dose vials at 2°C to 8°C, and use within 30 days.

Methotrexate Injection is a hazardous drug. Follow applicable special handling and disposal procedures.1

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