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mannitol injection, USP Description


Mannitol Injection, USP is a sterile, nonpyrogenic solution of mannitol in water for injection available in a fliptop vial for intravenous administration as an osmotic diuretic.

The content and characteristics are as follows:

Conc. (%)g/100 mLmOsmol/liter (calc.)pH*
May contain sodium bicarbonate and/or hydrochloric acid for pH adjustment.
252513725.9 (4.5 to 7.0)

The solution contains no bacteriostat, antimicrobial agent, or added buffer (except for pH adjustment) and is intended only as a single-dose injection.

Mannitol, USP is chemically designated D-mannitol (C6H14O6), a white crystalline powder or free-flowing granules freely soluble in water. It has the following structural formula:

Chemical Structure

Water for Injection, USP is chemically designated H2O.

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