11 DESCRIPTION
Mannitol Injection, USP is a sterile, nonpyrogenic solution of mannitol in water for injection available in a fliptop vial for intravenous administration as an osmotic diuretic.
The content and characteristics are as follows:
Conc. (%) | g/100 mL | mOsmol/liter (calc.) | pH* |
---|---|---|---|
| |||
25 | 25 | 1372 | 5.9 (4.5 to 7.0) |
The solution contains no bacteriostat, antimicrobial agent, or added buffer (except for pH adjustment) and is intended only as a single-dose injection.
Mannitol, USP is chemically designated D-mannitol (C6H14O6), a white crystalline powder or free-flowing granules freely soluble in water. It has the following structural formula:

Water for Injection, USP is chemically designated H2O.