6 ADVERSE REACTIONS
The following adverse reactions have been identified in clinical studies or postmarketing reports. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
Cardiovascular: | hypotension, circulatory collapse, cardiac depression including bradycardia |
Central Nervous System: | central nervous system depression leading to respiratory paralysis, visual disturbances, flushing, sweating, hypothermia |
Metabolic: | hypocalcemia with signs of tetany, hypermagnesemia |
Neurologic: | lethargy, sedation, somnolence, myasthenic crisis |
Neuromuscular: | depressed deep tendon reflexes, flaccid paralysis |
Pulmonary: | decreased respiratory rate, pulmonary edema |