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magnesium sulfate in 5% dextrose injection, USP

If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.

Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.

magnesium sulfate in 5% dextrose injection, USP Quick Finder

HIGHLIGHTS OF PRESCRIBING INFORMATION

These highlights do not include all the...
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1 INDICATIONS AND USAGE

Magnesium Sulfate in 5% Dextrose Injection is indicated for:

  • Prevention of eclampsia in patients with preeclampsia
  • Treatment of seizures and prevention of recurrent...
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2 DOSAGE AND ADMINISTRATION

2.1 Important Administration Instructions

Magnesium Sulfate in 5% Dextrose Injection is:

  • A clear solution....
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3 DOSAGE FORMS AND STRENGTHS

Magnesium Sulfate in 5% Dextrose Injection, USP is a clear and colorless to slightly yellow solution supplied in single-dose bags:

  • 0.01 grams per mL (1%):...
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4 CONTRAINDICATIONS

Magnesium Sulfate in 5% Dextrose Injection is contraindicated in patients:

  • with heart block or myocardial damage
  • in diabetic coma
  • with myasthenia gravis...
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5 WARNINGS AND PRECAUTIONS

5.1 Fetal-Neonatal Toxicity with Prolonged Use

Continuous administration of magnesium sulfate beyond 5 to 7 days in pregnant women can lead...

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6 ADVERSE REACTIONS

The following adverse reactions have been identified in clinical studies or postmarketing reports. Because these reactions are reported voluntarily from a population of uncertain size, it is not always...

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7 DRUG INTERACTIONS

Table 1 presents the potential clinical impact of medications that may be commonly administered concomitantly with Magnesium Sulfate in 5% Dextrose Injection in the clinical setting.

...
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8 USE IN SPECIFIC POPULATIONS

8.1 Pregnancy

Risk Summary

Magnesium Sulfate in 5...

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10 OVERDOSAGE

Manifestations of magnesium toxicity include a drop in blood pressure, difficulty breathing, and disappearance of the patellar reflex. As serum magnesium rises above 4 mEq per liter, the deep tendon reflexes...

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11 DESCRIPTION

Magnesium Sulfate in 5% Dextrose Injection, USP is a sterile, nonpyrogenic solution of magnesium sulfate heptahydrate and dextrose in water for injection for intravenous use. Each 100 mL contains 1 gram of...

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12 CLINICAL PHARMACOLOGY

12.1 Mechanism of Action

Magnesium prevents seizures in patients with preeclampsia and controls seizures in patients with eclampsia by...

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13 NONCLINICAL TOXICOLOGY

13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility

Studies with Magnesium Sulfate in 5% Dextrose Injection have not been performed to...

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16 HOW SUPPLIED/STORAGE AND HANDLING

Magnesium Sulfate in 5% Dextrose Injection, USP is a clear solution supplied in single-dose flexible plastic containers (see

Table 2: How Supplied...
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17 PATIENT COUNSELING INFORMATION

Magnesium Sulfate in 5% Dextrose Injection is typically administered to pregnancy women in emergent situations. When feasible, advise the patient and family of the following:

...
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