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lorazepam injection, USP VIAL

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Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.

lorazepam injection, USP VIAL Quick Finder

WARNING: RISKS FROM CONCOMITANT USE WITH OPIOIDS; ABUSE, MISUSE, AND ADDICTION; and DEPENDENCE AND WITHDRAWAL REACTIONS

  • Concomitant use of benzodiazepines and opioids may result in profound sedation...
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INDICATIONS AND USAGE

Status Epilepticus

Lorazepam injection is indicated for the treatment of status epilepticus.

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DOSAGE AND ADMINISTRATION

NOTE: CONTAINS BENZYL ALCOHOL (see

Status Epilepticus

General Advice

Status epilepticus is a...

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CONTRAINDICATIONS

Lorazepam injection is contraindicated in patients with a known sensitivity to benzodiazepines or its vehicle (polyethylene glycol, propylene glycol, and benzyl alcohol), in patients with acute narrow-angle...

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WARNINGS

Risks from Concomitant Use with Opioids

Concomitant use of benzodiazepines, including Lorazepam injection, and opioids may result in profound sedation,...

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ADVERSE REACTIONS

Status Epilepticus

The most important adverse clinical event caused by the use of Lorazepam injection is respiratory depression (see...

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DRUG ABUSE AND DEPENDENCE

Controlled Substance

Lorazepam injection contains lorazepam, a Schedule IV controlled substance.

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OVERDOSAGE

Symptoms

Overdosage of benzodiazepines is usually manifested by varying degrees of central-nervous-system depression, ranging from drowsiness to coma. In...

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DESCRIPTION

Lorazepam, a benzodiazepine with antianxiety, sedative, and anticonvulsant effects, is intended for the intramuscular or intravenous routes of administration. It has the chemical formula: 7-chloro-5(2-chlorophenyl...

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CLINICAL PHARMACOLOGY

Lorazepam interacts with the γ-aminobutyric acid (GABA)-benzodiazepine receptor complex, which is widespread in the brain of humans as well as other species. This interaction is presumed to be...

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ANIMAL TOXICOLOGY AND/OR PHARMACOLOGY

Published studies in animals demonstrate that the use of anesthetic agents during the period of rapid brain growth or synaptogenesis results in widespread neuronal and oligodendrocyte...

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HOW SUPPLIED

Lorazepam injection, USP is supplied as follows:

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Total Lorazepam
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CIV

For intravenous and intramuscular use
NOT FOR USE IN NEONATES
CONTAINS BENZYL ALCOHOL

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