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HEXTEND (6% Hetastarch in Lactated Electrolyte Injection)

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HEXTEND Quick Finder

WARNING: MORTALITY
RENAL REPLACEMENT THERAPY

In critically ill adult patients, including patients with sepsis, use of hydroxyethyl starch (HES) products, including HEXTEND, increases the risk of
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Mortality
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INDICATIONS AND USAGE

HEXTEND (6% Hetastarch in Lactated Electrolyte Injection) is indicated in the treatment of hypovolemia when plasma volume expansion is desired. It is not a substitute for blood or plasma.

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DOSAGE AND ADMINISTRATION

Dosage for Acute Use in Plasma Volume Expansion

HEXTEND is administered by intravenous infusion only. Total dosage and rate of infusion...

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------------------------------------------------CONTRAINDICATIONS----------------------------------------------

Do not use hydroxyethyl starch (HES) products, including HEXTEND, in critically ill adult patients, including...
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------------------------------------------WARNINGS AND PRECAUTIONS--------------------------------------

Avoid use in patients with pre-existing renal dysfunction
Discontinue use of HEXTEND at the first...
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-------------------------------------------------ADVERSE REACTIONS---------------------------------------------

Serious adverse reactions (ARs) observed in clinical trials of critically ill adult patients include:

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HEXTEND® (6% Hetastarch in Lactated Electrolyte Injection) is a sterile, nonpyrogenic solution for intravenous administration. The composition, pH, and osmolarity are given in

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CLINICAL PHARMACOLOGY

The plasma volume expansion produced by HEXTEND approximates that produced by 6% Hetastarch in 0.9% Sodium Chloride Injection and the plasma volume expansion of 6% Hetastarch in 0.9% Sodium Chloride...

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--------------------------------------------------CLINICAL STUDIES------------------------------------------------

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the...

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HOW SUPPLIED

HEXTEND (6% Hetastarch in Lactated Electrolyte Injection) is supplied sterile and nonpyrogenic in 500 mL single-dose flexible plastic infusion containers.

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6% Hetastarch in Lactated Electrolyte Injection

Flexible Plastic...

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