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furosemide injection, USP ANSYR Description

DESCRIPTION

Furosemide is a diuretic which is an anthranilic acid derivative. Chemically, it is 4‑chloro-N-furfuryl-5‑sulfamoylanthranilic acid.

Furosemide Injection 10 mg/mL is a sterile, non‑pyrogenic solution in an Ansyr™ plastic syringe for intravenous and intramuscular injection. Furosemide is a white to slightly-yellow crystalline powder. It is practically insoluble in water, sparingly soluble in alcohol, freely soluble in dilute alkali solutions and insoluble in dilute acids. The structural formula is as follows:

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Molecular formula: C12H11CIN2O5S Molecular weight: 330.74

Each mL contains: Furosemide 10 mg, Water for Injection q.s., Sodium Chloride for isotonicity, Sodium Hydroxide and, if necessary, Hydrochloric Acid to adjust pH between 8.0 and 9.3.

The plastic syringe is molded from a specially formulated polypropylene. Water permeates from inside the container at an extremely slow rate which will have an insignificant effect on solution concentration over the expected shelf life.

Solutions in contact with the plastic container may leach out certain chemical components from the plastic in very small amounts; however, biological testing was supportive of the safety of the syringe material.

Contains no preservative.

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