CONTRAINDICATIONS
ESTRING is contraindicated in women with any of the following conditions:
- 1.
- Undiagnosed abnormal genital bleeding.
- 2.
- Known, suspected, or history of breast cancer.
- 3.
- Known or suspected estrogen-dependent neoplasia.
- 4.
- Active DVT, PE, or a history of these conditions.
- 5.
- Active arterial thromboembolic disease (for example, stroke and MI), or a history of these conditions.
- 6.
- Known anaphylactic reaction or angioedema or hypersensitivity to ESTRING.
- 7.
- Known liver impairment or disease.
- 8.
- Known protein C, protein S, or antithrombin deficiency, or other known thrombophilic disorders.
- 9.
- Known or suspected pregnancy.