7 DRUG INTERACTIONS
7.1 Drugs Antagonizing Pressor Effects of Epinephrine
- α-blockers, such as phentolamine
- Vasodilators, such as nitrates
- Diuretics
- Antihypertensives
- Ergot alkaloids
- Phenothiazine antipsychotics
7.2 Drugs Potentiating Pressor Effects of Epinephrine
- Sympathomimetics
- β-blockers, such as propranolol
- Tricyclic anti-depressants
- Monoamine oxidase (MAO) inhibitors
- Catechol-O-methyl transferase (COMT) inhibitors, such as entacapone
- Clonidine
- Doxapram
- Oxytocin
7.3 Drugs Potentiating Arrhythmogenic Effects of Epinephrine
Patients who are concomitantly receiving any of the following drugs should be observed carefully for the development of cardiac arrhythmias [see Warnings and Precautions (5.5) and Adverse Reactions (6)].
- β-blockers, such as propranolol
- Cyclopropane or halogenated hydrocarbon anesthetics, such as halothane
- Antihistamines
- Thyroid hormones
- Diuretics
- Cardiac glycosides, such as digitalis glycosides
- Quinidine