2 DOSAGE AND ADMINISTRATION
2.1 Treatment of Moderate to Severe Vasomotor Symptoms Associated with Menopause
The recommended dosage is one DUAVEE tablet daily.
2.3 General Dosing Information
Take DUAVEE once daily, without regard to meals. Tablets should be swallowed whole.
2.4 Recommendations for Calcium and Vitamin D Supplementation
Women taking DUAVEE for prevention of postmenopausal osteoporosis should add supplemental calcium and/or vitamin D to their diet if daily intake is inadequate.
2.5 Administration Instructions for Missed Doses
If a dose of DUAVEE is missed, instruct patients to take it as soon as remembered unless it is almost time for the next scheduled dose. They should not take two doses at the same time.
2.6 Use in Patients with Renal Impairment
The pharmacokinetics of DUAVEE have not been evaluated in patients with renal impairment. Use in patients with renal impairment is not recommended [see Use in Specific Populations (8.6) and Clinical Pharmacology (12.3)].