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DIPHENOXYLATE Hydrochloride AND ATROPINE Sulfate Tablets, C-V (GREENSTONE LLC) Contraindications


Diphenoxylate hydrochloride and atropine sulfate is contraindicated in:

  • Pediatric patients less than 6 years of age due to the risks of respiratory and central nervous system (CNS) depression (see WARNINGS).
  • Patients with diarrhea associated with pseudomembranous enterocolitis (Clostridium difficile) or other enterotoxin-producing bacteria due to the risk of gastrointestinal (GI) complications, including sepsis (see WARNINGS).
  • Patients with known hypersensitivity to diphenoxylate or atropine.
  • Patients with obstructive jaundice.
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