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diltiazem hydrochloride for injection

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diltiazem hydrochloride for injection Quick Finder

INDICATIONS AND USAGE

Diltiazem Hydrochloride Injection or Diltiazem Hydrochloride for Injection are indicated for the following:

Atrial Fibrillation or Atrial Flutter...

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DOSAGE AND ADMINISTRATION

Direct Intravenous Single Injections (Bolus)

The initial dose of diltiazem hydrochloride injection should be 0.25 mg/kg actual body weight as...

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CONTRAINDICATIONS

Injectable forms of diltiazem are contraindicated in:

  1. Patients with sick sinus syndrome except in the presence of a functioning ventricular pacemaker.
  2. Patients with second...
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WARNINGS

  1. Cardiac Conduction. Diltiazem prolongs AV nodal conduction and refractoriness that may rarely result in second- or third-degree AV block in sinus rhythm. Concomitant use of diltiazem...
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ADVERSE REACTIONS

The following adverse reaction rates are based on the use of diltiazem hydrochloride injection in over 400 domestic clinical trial patients with atrial fibrillation/flutter or PSVT under double-blind or...

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OVERDOSAGE

Overdosage experience is limited. In the event of overdosage or an exaggerated response, appropriate supportive measures should be employed. The following measures may be considered:

...

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DESCRIPTION

Diltiazem hydrochloride is a calcium ion cellular influx inhibitor (slow channel blocker or calcium channel antagonist). Chemically, diltiazem hydrochloride is 1,5-benzothiazepin-4(5H...

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CLINICAL PHARMACOLOGY

Mechanisms of Action

Diltiazem inhibits the influx of calcium (Ca2+) ions during membrane depolarization of cardiac and...

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HOW SUPPLIED

Diltiazem Hydrochloride Injection is supplied in single-dose Fliptop vials as follows:

...
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INSTRUCTIONS FOR USE

To Use Vial in ADD-Vantage® Flexible Diluent Container

To Open:

Peel overwrap at corner...

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Single-Dose Fliptop Vial

Diltiazem Hydrochloride for Injection
Single-Dose ADD-Vantage® Vial...

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