INDICATIONS AND USAGE
Diltiazem Hydrochloride Injection or Diltiazem Hydrochloride for Injection are indicated for the following:
Atrial Fibrillation or Atrial Flutter...
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diltiazem hydrochloride for injection
If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.
Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.
diltiazem hydrochloride for injection Quick Finder
Dosage and Administration
DOSAGE AND ADMINISTRATION
Direct Intravenous Single Injections (Bolus)
The initial dose of diltiazem hydrochloride injection should be 0.25 mg/kg actual body weight as...
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Contraindications
CONTRAINDICATIONS
Injectable forms of diltiazem are contraindicated in:
- Patients with sick sinus syndrome except in the presence of a functioning ventricular pacemaker.
- Patients with second...
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Warnings and Precautions
WARNINGS
- Cardiac Conduction. Diltiazem prolongs AV nodal conduction and refractoriness that may rarely result in second- or third-degree AV block in sinus rhythm. Concomitant use of diltiazem...
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Adverse Reactions
ADVERSE REACTIONS
The following adverse reaction rates are based on the use of diltiazem hydrochloride injection in over 400 domestic clinical trial patients with atrial fibrillation/flutter or PSVT under double-blind or...
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Overdosage
OVERDOSAGE
Overdosage experience is limited. In the event of overdosage or an exaggerated response, appropriate supportive measures should be employed. The following measures may be considered:
...
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Description
DESCRIPTION
Diltiazem hydrochloride is a calcium ion cellular influx inhibitor (slow channel blocker or calcium channel antagonist). Chemically, diltiazem hydrochloride is 1,5-benzothiazepin-4(5H...
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Clinical Pharmacology
CLINICAL PHARMACOLOGY
Mechanisms of Action
Diltiazem inhibits the influx of calcium (Ca2+) ions during membrane depolarization of cardiac and...
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How Supplied/Storage and Handling
HOW SUPPLIED
Diltiazem Hydrochloride Injection is supplied in single-dose Fliptop vials as follows:
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Instructions For Use
INSTRUCTIONS FOR USE
To Use Vial in ADD-Vantage® Flexible Diluent Container
To Open:
Peel overwrap at corner...
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Report Adverse Event
To report an adverse event related to Pfizer-BioNTech COVID-19 Vaccine (also known as COMIRNATY®, COVID-19 mRNA, Vaccine BNT162b2 or BNT162) or Pfizer COVID-19 Treatment (also known as PAXLOVID™ (nirmatrelvir tablets; ritonavir tablets)), and you are not part of a clinical trial* for this product, click the link below to submit your information:
*If you are involved in a clinical trial for either product, adverse events should be reported to your coordinating study site.
If you cannot use the above website or would like to report an adverse event related to a different Pfizer product, please call Pfizer Safety at(800) 438-1985.
You may also contact the U.S. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns either online at www.fda.gov/medwatchor by calling
(800)-332-1088.
(800)-332-1088.